Harnessing the therapeutic potential of biomacromolecules through intracellular delivery of nucleic acids, peptides, and proteins

Y Tian, MV Tirrell, JL LaBelle - Advanced healthcare materials, 2022 - Wiley Online Library
Biomacromolecules have long been at the leading edge of academic and pharmaceutical
drug development and clinical translation. With the clinical advances of new therapeutics …

Design of biomaterials through direct ring-opening metathesis polymerisation of functionalised cyclic alkenes

S Kobayashi, M Tanaka - Molecular Systems Design & Engineering, 2023 - pubs.rsc.org
Ring-opening metathesis polymerisation (ROMP) has become a popular method for
synthesising complex functional polymers owing to the high functional group tolerance of …

Effects of Ionic Strength on the Morphology, Scattering, and Mechanical Response of Neurofilament-Derived Protein Brushes

TJ Yokokura, C Duan, EA Ding, S Kumar… - …, 2023 - ACS Publications
Protein brushes not only play a key role in the functionality of neurofilaments but also have
wide applications in biomedical materials. Here, we investigate the effect of ionic strength on …

Molecular brushes based on poly (amino acid) s: synthesis, structures, and applications

Y Feng, C Wei, T Zhao - Journal of Polymer Science, 2024 - Wiley Online Library
Polymer science is witnessing rapid advancements in the precision construction of synthetic
macromolecules. Beyond the impressive advances in molecular brush, the integration of …

Recent Advances in Drug Release, Sensing, and Cellular Uptake of Ring-Opening Metathesis Polymerization (ROMP) Derived Poly (olefins)

UR Gandra, SK Podiyanachari, HS Bazzi… - ACS …, 2023 - ACS Publications
The synthesis and applications of ring-opening metathesis polymerization (ROMP) derived
poly (olefins) have emerged as an exciting area of great interest in the field of biomaterials …