[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives
H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …
An insight on ophthalmic drug delivery systems: focus on polymeric biomaterials-based carriers
Presently, different types of eye diseases, such as glaucoma, myopia, infection, and dry eyes
are treated with topical eye drops. However, due to ocular surface barriers, eye drops …
are treated with topical eye drops. However, due to ocular surface barriers, eye drops …
Multifaceted roles of pollen in the management of cancer
Oral drug delivery of microparticles demonstrates shortcomings like aggregation, decreased
loading capacity and batch-to-batch variation, which limits its scale-up. Later, porous …
loading capacity and batch-to-batch variation, which limits its scale-up. Later, porous …
Emerging trends in nano-based antidiabetic therapeutics: a path to effective diabetes management
Diabetes mellitus is characterized by altered blood sugar homeostasis. Diabetic mortality
rates are escalating in developed countries by the day. Currently, no effective treatment and …
rates are escalating in developed countries by the day. Currently, no effective treatment and …
Chitosan-coated bovine serum albumin nanoparticles for topical tetrandrine delivery in glaucoma: in vitro and in vivo assessment
Glaucoma is one of the leading causes of blindness. Therapies available suffer from several
drawbacks including low bioavailability, repeated administration and poor patient …
drawbacks including low bioavailability, repeated administration and poor patient …
Hyaluronic acid: Its versatile use in ocular drug delivery with a specific focus on hyaluronic acid-based polyelectrolyte complexes
S Casey-Power, R Ryan, G Behl, P McLoughlin… - Pharmaceutics, 2022 - mdpi.com
Extensive research is currently being conducted into novel ocular drug delivery systems
(ODDS) that are capable of surpassing the limitations associated with conventional …
(ODDS) that are capable of surpassing the limitations associated with conventional …
Overcoming Treatment Challenges in Posterior Segment Diseases with Biodegradable Nano-Based Drug Delivery Systems
KY Wu, M Joly-Chevrier, D Akbar, SD Tran - Pharmaceutics, 2023 - mdpi.com
Posterior segment eye diseases present a challenge in treatment due to the complex
structures in the eye that serve as robust static and dynamic barriers, limiting the penetration …
structures in the eye that serve as robust static and dynamic barriers, limiting the penetration …
Preparation, physicochemical, and retinal anti-angiogenic evaluation of poloxamer hydrogel containing dexamethasone/avastin-loaded chitosan-N-acetyl-L-cysteine …
SL Taheri, M Rezazadeh, F Hassanzadeh… - International Journal of …, 2022 - Elsevier
This study was meant to describe a Poloxamer hydrogel combining Chitosan-N-acetyl-L-
cysteine (CNAC) nanoparticles to increase loading and sustained intravitreal administration …
cysteine (CNAC) nanoparticles to increase loading and sustained intravitreal administration …
Recent advances of ocular drug delivery systems: prominence of ocular implants for chronic eye diseases
Chronic ocular diseases can seriously impact the eyes and could potentially result in
blindness or serious vision loss. According to the most recent data from the WHO, there are …
blindness or serious vision loss. According to the most recent data from the WHO, there are …
Emerging treatment strategies for diabetes mellitus and associated complications: an update
The occurrence of diabetes mellitus (DM) is increasing rapidly at an accelerating rate
worldwide. The status of diabetes has changed over the last three generations; whereas …
worldwide. The status of diabetes has changed over the last three generations; whereas …