Platelets produce platelet growth factors such as PDGF, IGF-1, EGF-, HGF, TGFβ, bFGF, and
VEGF, which are crucial in regulating all stages of the wound healing process. The source of …

Osteoarthritis (OA) is a prevalent chronic whole-joint disease characterized by low-grade
systemic inflammation, degeneration of joint-related tissues such as articular cartilage, and …

This review is based on a systematic review of the literature relevant to clinical topics in
osteoarthritis (OA) performed for the time period February 22, 2016 to April 1, 2017. A …

Background: Platelet-rich plasma (PRP) injections have been proposed as a new
conservative option for knee degeneration to provide symptomatic relief and delay surgical …

Objective To evaluate effectiveness, in terms of patient-reported outcome measures, of
platelet-rich plasma (PRP) injections for knee osteoarthritis compared to placebo and other …

Background Quite a few randomized controlled trials (RCTs) investigating the efficacy of
platelet-rich plasma (PRP) for treatment of knee osteoarthritis (OA) have been recently …

The clinical application of platelet-rich plasma (PRP) and other regenerative therapies in
sports, spine, and musculoskeletal medicine has soared in the last decade. Over this period …

Background Platelet-rich plasma (PRP) provides a nonsurgical approach for treating
osteoarthritis (OA). Exosomes that play vital roles in intercellular communication have been …

Background Knee osteoarthritis (KOA) is a degenerative joint disease leading to pain and
disability for which no curative treatment exists. Intra-articular (IA) therapies are part of this …

Platelet-rich plasma (PRP) is defined as a volume of plasma with a platelet concentration
higher than the average in peripheral blood. Many basic, preclinical and even clinical case …