Cells navigate environments, communicate and build complex patterns by initiating gene
expression in response to specific signals. Engineers seek to harness this capability to …

Cells live in an ever-changing environment and continuously sense, process and react to
environmental signals using their inherent signaling and gene regulatory networks …

Modular and orthogonal genetic logic gates are essential for building robust biologically
based digital devices to customize cell signalling in synthetic biology. Here we constructed …

One challenge for synthetic biologists is the predictable tuning of genetic circuit regulatory
components to elicit desired outputs. Gene expression driven by ligand-inducible …

Synthetic genetic sensors and circuits enable programmable control over the timing and
conditions of gene expression. They are being increasingly incorporated into the control of …

In prokaryotes, the construction of synthetic, multi-input promoters is constrained by the
number of transcription factors that can simultaneously regulate a single promoter. This …

We developed a bacteria-based AND logic gate using a Pseudomonas aeruginosa lasI/rhlI
double mutant with two quorum-sensing signaling molecules as the input signals. We …

Cell-cell communication is a widespread phenomenon in nature, ranging from bacterial
quorum sensing and fungal pheromone communication to cellular crosstalk in multicellular …

This paper presents novel implementations for reservoir computing (RC) using DNA
oscillators. An RC system consists of two parts: reservoir and readout layer. The reservoir …

One of the visions of synthetic biology is to be able to program cells using a language that is
similar to that used to program computers or robotics. For large genetic programs, keeping …