Regional variability in therapeutic hypothermia eligibility criteria for neonatal hypoxic-ischemic encephalopathy

J Proietti, GB Boylan, BH Walsh - Pediatric Research, 2024 - nature.com
Early induced therapeutic hypothermia represents the cornerstone treatment in neonates
with probable hypoxic-ischemic encephalopathy. The selection of patients for treatment …

Prognostic value of quantitative EEG in early hours of life for neonatal encephalopathy and neurodevelopmental outcomes

S Kota, S Kang, YL Liu, H Liu, S Montazeri… - Pediatric …, 2024 - nature.com
Background The ability to determine severity of encephalopathy is crucial for early
neuroprotective therapies and for predicting neurodevelopmental outcome. The objective of …

Differences in standardized neonatal encephalopathy exam criteria may impact therapeutic hypothermia eligibility

BH Walsh, H El-Shibiny, C Munster, E Yang… - Pediatric …, 2022 - nature.com
Background Therapeutic hypothermia (TH) is routinely provided to those with moderate or
severe neonatal encephalopathy (NE). Subtle differences exist in the standardized exams …

Establishing a regional registry for neonatal encephalopathy: impact on identification of gaps in practice

M El-Dib, H El-Shibiny, B Walsh, S Cherkerzian… - Pediatric …, 2024 - nature.com
Background Neonatal encephalopathy (NE) continues to be a significant risk for death and
disability. To address this risk, regional guidelines were developed with the support of a …

Amplitude-integrated electroencephalography evolution and magnetic resonance imaging injury in mild and moderate to severe neonatal encephalopathy

K Sakpichaisakul, M El-Dib, C Munster… - American Journal of …, 2023 - thieme-connect.com
Objective This study aimed to describe the evolution of amplitude-integrated
electroencephalography (aEEG) in neonatal encephalopathy (NE) during therapeutic …

Is there a problem with how we select patients for therapeutic hypothermia?

ER Gunn, MR Battin, AJ Gunn - Pediatric Research, 2024 - nature.com
It has been over a decade since therapeutic hypothermia (TH) was shown in multiple large
randomized controlled trials to improve the survival without disability after moderate-to …

Patterns of acute kidney and hepatic injury and association with adverse outcomes in infants undergoing therapeutic hypothermia for hypoxic ischemic …

AK Modisett, RM Patel, SM Jernigan, J Figueroa… - Journal of …, 2022 - nature.com
Objective To describe patterns of renal and hepatic injury in infants with hypoxic ischemic
encephalopathy (HIE). Study design Retrospective cohort of infants receiving therapeutic …

Hypoxic-Ischemic Injury in the Term Infant: Clinical-Neurological Features, Diagnosis, Imaging, Management, and Prognosis

A Mrelashvili, D Ferriero, TE Inder, JJ Volpe - Volpe's Neurology of the …, 2025 - Elsevier
Neonatal encephalopathy occurs in 2 to 6/1000 live births and is principally related to
hypoxic-ischemic injury to the newborn brain in the immediate peripartum period. In the first …

Evolution of the Sarnat exam and association with 2-year outcomes in infants with moderate or severe hypoxic-ischaemic encephalopathy: a secondary analysis of the …

U Mietzsch, SE Kolnik, TR Wood, N Natarajan… - Archives of Disease in …, 2024 - fn.bmj.com
Objective To study the association between the Sarnat exam (SE) performed before and
after therapeutic hypothermia (TH) and outcomes at 2 years in infants with moderate or …

[HTML][HTML] Escenarios para el diagnóstico de encefalopatía hipóxico isquémica e inicio de tratamiento con hipotermia controlada en recién nacidos con asfixia perinatal

F Silvera, JP Gesuele, L Lucas, G Vidal… - Archivos de Pediatría …, 2024 - scielo.edu.uy
La hipoxia isquemia perinatal y su complicación más temida, la encefalopatía hipóxica
isquémica, continúa siendo uno de los principales motivos de ingreso a las unidades de …