During the last years, studies investigating the intriguing association between
immunodeficiency and autoimmunity led to the discovery of new monogenic disorders, the …

Common variable immunodeficiency (CVID) is the most common symptomatic primary
immunodeficiency (PID). CVID is a heterogenous condition and clinical manifestations may …

Objective To evaluate the characteristics of patients with autoimmune disease with
hypogammaglobulinemia following rituximab (RTX) and describe their long-term outcomes …

Background Tertiary lymphoid structures (TLSs) are immune aggregates in peripheral
tissues that may support adaptive immune responses. Their presence has been associated …

Common variable immunodeficiency (CVID) is the most common clinically significant
primary immunodeficiency in adulthood, which presents a broad spectrum of clinical …

The risk of severe adult respiratory coronavirus-2 (SARS-CoV-2) infection and the course of
the infection among individuals with common variable immunodeficiency (CVID) relative to …

Inborn errors of immunity (IEI) are genetic disorders characterized by a wide spectrum of
clinical manifestations, ranging from increased susceptibility to infections to significant …

Objective To summarize the current understanding of diagnostic and postdiagnostic
evaluation of common variable immunodeficiency (CVID). Data Sources PubMed Central …

The IL-2 family of cytokines act via receptor complexes that share the interleukin-2 receptor
gamma common (IL-2Rγc) chain to play key roles in lymphopoiesis. Inactivating IL-2Rγc …

Common variable immunodeficiency (CVID) is the most frequently diagnosed primary
antibody deficiency. About half of CVID patients develop chronic non-infectious …