Highlights•Recurrent connectivity is anatomically and functionally prevalent in fly memory
circuits.•Sustained reverberant activity is necessary for memory consolidation.•Feedforward …

New approaches, techniques and tools invented over the last decade and a half have
revolutionized the functional dissection of neural circuitry underlying Drosophila learning …

Making inferences about the computations performed by neuronal circuits from synapse-
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …

Understanding memory formation, storage and retrieval requires knowledge of the
underlying neuronal circuits. In Drosophila, the mushroom body (MB) is the major site of …

Animals discriminate stimuli, learn their predictive value and use this knowledge to modify
their behavior. In Drosophila, the mushroom body (MB) plays a key role in these processes …

Dopamine is synonymous with reward and motivation in mammals,. However, only recently
has dopamine been linked to motivated behaviour and rewarding reinforcement in fruitflies …

During olfactory learning in fruit flies, dopaminergic neurons assign value to odor
representations in the mushroom body Kenyon cells. Here we identify a class of downstream …

Sparse coding may be a general strategy of neural systems for augmenting memory
capacity. In Drosophila melanogaster, sparse odor coding by the Kenyon cells of the …

Animals acquire predictive values of sensory stimuli through reinforcement. In the brain of
Drosophila melanogaster, activation of two types of dopamine neurons in the PAM and …

Resource-seeking behaviours are ordinarily constrained by physiological needs and threats
of danger, and the loss of these controls is associated with pathological reward seeking …