Epigenetics is defined as heritable changes to the transcriptome that are independent of
changes in the genome. The biochemical modifications that govern epigenetics are DNA …

CONTEXT: Despite widespread screening for prostate cancer (PCa) and major advances in
the treatment of metastatic disease, PCa remains the second most common cause of cancer …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
progressive loss of motor neurons. Using unbiased transcript profiling in an ALS mouse …

Microarrays have become a routine tool for biomedical research. Data quality assessment is
an essential part of the analysis, but it is still not easy to perform objectively or in an …

Prostate cancer (PCa) is currently the most frequently diagnosed malignancy in the western
countries. It is more prevalent in older men with 75% of the incident cases above 65 years …

PURPOSE:: Abnormal miRNA expression has emerged as crucial factors in carcinogenesis
and is important in the comprehension of prostate cancer behavior. We determined the …

Cancer in humans is the result of a multi-step process. This process often involves the
activation of oncogenes and/or the inactivation of tumor suppressor genes. These two steps …

Background Despite recent progress in the identification of genetic and molecular
alterations in prostate cancer, markers associated with tumor progression are scarce …

Background Prostate cancer (PCa) is the most commonly diagnosed malignancy in men
who are especially over the age of 50 years in the western countries. Currently used …

Molecular markers predictive of prostate cancer prognosis are urgently needed.
Overexpression of the antiapoptotic protein, Bcl‐2, has repeatedly been shown to be …