An increasing number of epilepsies are being attributed to variants in genes with epigenetic
functions. The products of these genes include factors that regulate the structure and …

Nearly 7 decades have elapsed since Francis Crick introduced the central dogma of
molecular biology, as part of his ideas on protein synthesis, setting the fundamental rules of …

In most organisms, the whole genome is maintained throughout the life span. However,
exceptions occur in some species where the genome is reduced during development …

High Mobility Group Box (HMGB) proteins are small architectural DNA binding proteins that
regulate multiple genomic processes such as DNA damage repair, nucleosome sliding …

BACKGROUND Uterine leiomyomas, also known as uterine fibroids or myomas, are the
most common benign gynecological tumors and are found in women of reproductive and …

Plants have developed multiple mechanisms as an adaptive response to abiotic stresses,
such as salinity, drought, heat, cold, and oxidative stress. Understanding these regulatory …

Histones display a wide variety of post-translational modifications, including acetylation,
methylation, and phosphorylation. These epigenetic modifications can influence chromatin …

Alzheimer's disease (AD) represents one of the most common and debilitating
neurodegenerative disorders. By the end of 2040, AD patients might reach 11.2 million in …

Architectural proteins are essential epigenetic regulators that play a critical role in
organizing chromatin and controlling gene expression. CTCF (CCCTC-binding factor) is a …

Inherent and acquired abnormalities in gene regulation due to the influence of genetics and
epigenetics (traits related to environment rather than genetic factors) underlie many …