Single-molecule super-resolution fluorescence microscopy and single-particle tracking are
two imaging modalities that illuminate the properties of cells and materials on spatial scales …

Super-resolution fluorescence imaging by photoactivation or photoswitching of single
fluorophores and position determination (single-molecule localization microscopy, SMLM) …

Nucleosomes help structure chromosomes by compacting DNA into fibers. To gain insight
into how nucleosomes are arranged in vivo, we combined quantitative super-resolution …

Since its initial demonstration in 2000, far-field super-resolution light microscopy has
undergone tremendous technological developments. In parallel, these developments have …

Super-resolution microscopy (SRM) methods have allowed scientists to exceed the
diffraction limit of light, enabling the discovery and investigation of cellular structures at the …

Rat sarcoma (Ras) GTPases regulate cell proliferation and survival through effector
pathways including Raf-MAPK, and are the most frequently mutated genes in human cancer …

Fluorescence imaging techniques play a pivotal role in our understanding of the nervous
system. The emergence of various super-resolution microscopy methods and specialized …

Tau is a microtubule-associated protein, which promotes neuronal microtubule assembly
and stability. Accumulation of tau into insoluble aggregates known as neurofibrillary tangles …

The recent 2014 Nobel Prize in chemistry honored an era of discoveries and technical
advancements in the field of super‐resolution microscopy. However, the applications of …

Immunolabeling and autoradiography have traditionally been applied as the methods-of-
choice to visualize and collect molecular information about physiological and pathological …