Although gray matter (GM) damages caused by long term and excessive alcohol
consumption have long been reported, the structural neuroimaging findings on alcohol-use …

Prefrontal cortical dysfunctions underlying inhibitory control deficits in addiction are complex
and likely dependent on population characteristics. Here, we conducted a meta-analysis to …

Интернет-зависимость (ИЗ) признана одним из распространенных вариантов
аддиктивных нарушений нехимической природы и имеет значительные негативные …

Background Alcohol use disorder (AUD) is associated with cognitive deficits such as
impaired executive functions, which are hypothesized to contribute to the progression of the …

A basic survival need is the ability to respond to, and persevere in the midst of, experiential
challenges. Mechanisms of neuroplasticity permit this responsivity via functional adaptations …

Positron emission tomography (PET) enables non-invasive estimation of neurotransmitter
fluctuations in the living human brain. While these methods have been applied to dopamine …

The medial prefrontal cortex (mPFC) plays an important role in high-order executive
processes and sends highly organized projections to sub-cortical regions controlling mood …

Drug addiction is a compulsive behavioral abnormality. In spite of pharmacological
treatments and psychosocial support to reduce or eliminate drug intake, addiction tends to …

Cognitive deficits are highly comorbid with substance use disorders. Deficits span multiple
cognitive domains, are associated with disease severity across substance classes, and …

Substance use disorders are chronic, relapsing, and harmful conditions characterized by
executive dysfunction. While there are currently no approved pharmacotherapy options for …