Over the past several decades, the incidence of early-onset cancers, often defined as
cancers diagnosed in adults< 50 years of age, in the breast, colorectum, endometrium …

Despite decades of laboratory, epidemiological and clinical research, breast cancer
incidence continues to rise. Breast cancer remains the leading cancer-related cause of …

A woman has an increased risk of breast cancer if her lifelong estrogen exposure is
increased due to an early menarche, a late menopause, and/or an absence of childbearing …

Background. The acceleration of pubertal development is an important medical and social
problem, as it may result in increased morbidity and mortality in later life. This systematic …

A 7 year old girl presents with history of body odour. She is tall for her age and her mother
reports noticeable breast development and pubic hair growth over the last six months. The …

Soybeans are a rich source of isoflavones, which are classified as phytoestrogens. Despite
numerous proposed benefits, isoflavones are often classified as endocrine disruptors, based …

Routine exposure to artificial light at night (ALAN) in work, home, and community settings is
linked with increased risk of breast and prostate cancer (BC, PC) in normally sighted women …

Soy is a hotly debated and widely discussed topic in the field of nutrition. However, health
practitioners may be ill-equipped to counsel clients and patients about the use of soyfoods …

MKRN3 mutations represent the most common genetic cause of central precocious puberty
(CPP) but associations between genotype and clinical features have not been extensively …

Menarche is the first occurrence of a woman's menstruation, an event that symbolizes
reproductive capacity and the transition from childhood into womanhood. The global …