Immune dysfunction in uremia 2020

G Cohen - Toxins, 2020 - mdpi.com
Cardiovascular disease and infections are major causes for the high incidence of morbidity
and mortality of patients with chronic kidney disease. Both complications are directly or …

Hydrogen sulfide biology and its role in cancer

S Khattak, MA Rauf, NH Khan, QQ Zhang, HJ Chen… - Molecules, 2022 - mdpi.com
Hydrogen sulfide (H2S) is an endogenous biologically active gas produced in mammalian
tissues. It plays a very critical role in many pathophysiological processes in the body. It can …

[HTML][HTML] Role of hydrogen sulfide donors in cancer development and progression

EE Ngowi, A Afzal, M Sarfraz, S Khattak… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
In recent years, a vast number of potential cancer therapeutic targets have emerged.
However, developing efficient and effective drugs for the targets is of major concern …

Metformin accelerates myelin recovery and ameliorates behavioral deficits in the animal model of multiple sclerosis via adjustment of AMPK/Nrf2/mTOR signaling and …

N Sanadgol, M Barati, F Houshmand, S Hassani… - Pharmacological …, 2020 - Springer
Background Multiple sclerosis (MS) is a devastating autoimmune disorder characterized by
oligodendrocytes (OLGs) loss and demyelination. In this study, we have examined the …

Circulating Levels of Hydrogen Sulfide (H2S) in Patients with Age-Related Diseases: A Systematic Review and Meta-Analysis

E Piragine, MA Malanima, E Lucenteforte, A Martelli… - Biomolecules, 2023 - mdpi.com
Hydrogen sulfide (H2S) is an endogenous gasotransmitter that promotes multiple biological
effects in many organs and tissues. An imbalanced biosynthesis of H2S has been observed …

Roles of hydrogen sulfide donors in common kidney diseases

EE Ngowi, M Sarfraz, A Afzal, NH Khan… - Frontiers in …, 2020 - frontiersin.org
Hydrogen sulfide (H2S) plays a key role in the regulation of physiological processes in
mammals. The decline in H2S level has been reported in numerous renal disorders. In …

An updated review of various medicinal applications of p-Co umaric acid: From antioxidative and anti-inflammatory properties to effects on cell cycle and proliferation

MF Abazari, N Nasiri, SZ Karizi, F Nejati… - Mini reviews in …, 2021 - ingentaconnect.com
P-Coumaric acid (p-CA) is a hydroxycinnamic acid, an organic compound that is a hydroxyl
derivative of cinnamic acid. P-CA is the most abundant isomer in nature and can be found in …

The roles of hydrogen sulfide in renal physiology and disease states

J Feng, X Lu, H Li, S Wang - Renal Failure, 2022 - Taylor & Francis
Abstract Hydrogen sulfide (H2S), an endogenous gaseous signaling transmitter, has gained
recognition for its physiological effects. In this review, we aim to summarize and discuss …

Mechanisms and pathogenesis underlying environmental chemical-induced necroptosis

MR Sepand, M Aliomrani, Y Hasani-Nourian… - … Science and Pollution …, 2020 - Springer
Necroptosis is a regulated cell death that is governed by mixed lineage kinase domain-like,
receptor-interacting serine-threonine kinase 3 and commonly displays with necrosis …

SG1002 and catenated divalent organic sulfur compounds as promising hydrogen sulfide prodrugs

G Gojon, GA Morales - Antioxidants & Redox Signaling, 2020 - liebertpub.com
Significance: Sulfur has a critical role in protein structure/function and redox status/signaling
in all living organisms. Although hydrogen sulfide (H2S) and sulfane sulfur (SS) are now …