Aims Patients with acute pulmonary embolism (PE) classified as low risk by the Pulmonary
Embolism Severity Index (PESI), its simplified version (sPESI), or the Hestia criteria may be …

Aim Thrombolytic therapy induces faster clot dissolution than anticoagulation in patients with
acute pulmonary embolism (PE) but is associated with an increased risk of haemorrhage …

Background The role of fibrinolytic therapy in patients with intermediate-risk pulmonary
embolism is controversial. Methods In a randomized, double-blind trial, we compared …

Background—In patients with acute pulmonary embolism, systemic thrombolysis improves
right ventricular (RV) dilatation, is associated with major bleeding, and is withheld in many …

The task of developing ESC Guidelines covers not only the integration of the most recent
research, but also the creation of educational tools and implementation programmes for the …

Objective To develop disease-specific recommendations for the diagnosis and management
of eosinophilic granulomatosis with polyangiitis (Churg–Strauss syndrome)(EGPA). Methods …

Objective: To establish evidence-based guidelines for the use of bedside cardiac
ultrasound, echocardiography, in the ICU and equivalent care sites. Methods: Grading of …

Background This article addresses the treatment of VTE disease. Methods We generated
strong (Grade 1) and weak (Grade 2) recommendations based on high-quality (Grade A) …

Background Apixaban, an oral factor Xa inhibitor that can be administered in a simple, fixed-
dose regimen, may be an option for the extended treatment of venous thromboembolism …

not override in any way whatsoever the individual responsibility of health professionals to
make appropriate and accurate decisions in consideration of each patient's health condition …