Benzothiazole is an organic compound bearing a heterocyclic nucleus (thiazole) which
imparts a broad spectrum of biological activities to it. The significant and potent activity of …

Background: Cancer is the second leading cause of death worldwide. Many anticancer
drugs are commercially available, but lack of selectivity, target specificity, cytotoxicity, and …

In this work, we report structural and computational studies of a series of naphthalene-based
bis-N-salicylidene aniline dyes, namely N, N′-bis-salicylidene-1, 5-diaminonaphthalene …

Cancer is a complex and heterogeneous disease and is still one of the leading causes of
morbidity and mortality worldwide, mostly as the population ages. Despite the encouraging …

Puerariae Radix (PR) is a natural herb whose active ingredient is mainly flavonoids. To
explore the interaction between PR flavonoids and DNA not only has important biological …

The resistance-nodulation-division (RND) family efflux pumps are important in the antibiotic
resistance of Gram-negative bacteria. However, although a number of bacterial RND efflux …

Abstract The coronavirus disease 2019 (COVID-19) pandemic has posed a threat to public
health throughout the world since the Severe Acute Respiratory Syndrome Coronavirus 2 …

Cancer is the third mostlethal disease in the world after cardiovascular,
parasiticandinfectious diseases, based on reports from American Cancer Society (ACS)[1 …

Human GSTP1-1 is one of the most important proteins, which overexpresses in a large
number of human tumours and is involved in the development of resistance to several …

Recently, NK1R (Neurokinin-1 receptors) take attention as new and promising target in
anticancer drug development area. It has been proved that non-peptide NK1R antagonists L …