Mechanisms and consequences of sex differences in immune responses
Biological sex differences refer to differences between males and females caused by the sex
chromosome complement (that is, XY or XX), reproductive tissues (that is, the presence of …
chromosome complement (that is, XY or XX), reproductive tissues (that is, the presence of …
Sex—the most underappreciated variable in research: insights from helminth-infected hosts
A Wesołowska - Veterinary Research, 2022 - Springer
The sex of a host affects the intensity, prevalence, and severity of helminth infection. In many
cases, one sex has been found to be more susceptible than the other, with the prevalence …
cases, one sex has been found to be more susceptible than the other, with the prevalence …
Sex-based differences in clearance of chronic Plasmodium falciparum infection
J Briggs, N Teyssier, JI Nankabirwa, J Rek… - Elife, 2020 - elifesciences.org
Multiple studies have reported a male bias in incidence and/or prevalence of malaria
infection in males compared to females. To test the hypothesis that sex-based differences in …
infection in males compared to females. To test the hypothesis that sex-based differences in …
[HTML][HTML] NK cells associate with ALS in a sex-and age-dependent manner
BJ Murdock, JP Famie, CE Piecuch, KD Pawlowski… - JCI insight, 2021 - ncbi.nlm.nih.gov
NK cells are innate immune cells implicated in ALS; whether NK cells impact ALS in a sex-
and age-specific manner was investigated. Herein, NK cells were depleted in male and …
and age-specific manner was investigated. Herein, NK cells were depleted in male and …
Malaria infection among adults residing in a highly endemic region from the Democratic Republic of the Congo
NK Kayiba, Y Nitahara, E Tshibangu-Kabamba… - Malaria Journal, 2024 - Springer
Abstract Background Adults infected with Plasmodium spp. in endemic areas need to be re-
evaluated in light of global malaria elimination goals. They potentially undermine malaria …
evaluated in light of global malaria elimination goals. They potentially undermine malaria …
Greater breadth of vaccine-induced immunity in females than males is mediated by increased antibody diversity in germinal center B cells
Inactivated influenza vaccines induce greater antibody responses in females than males
among both humans and mice. To test the breadth of protection, we used recombinant …
among both humans and mice. To test the breadth of protection, we used recombinant …
Estradiol mediates greater germinal center responses to influenza vaccination in female than male mice
Adult females of reproductive age develop greater antibody responses to inactivated
influenza vaccines (IIV) than males. How sex, age, and sex steroid concentrations impact B …
influenza vaccines (IIV) than males. How sex, age, and sex steroid concentrations impact B …
Needle-free, spirulina-produced Plasmodium falciparum circumsporozoite vaccination provides sterile protection against pre-erythrocytic malaria in mice
T Saveria, C Parthiban, AM Seilie, C Brady, A Martinez… - npj Vaccines, 2022 - nature.com
Antibodies against the Plasmodium falciparum circumsporozoite protein (PfCSP) can block
hepatocyte infection by sporozoites and protect against malaria. Needle-free vaccination …
hepatocyte infection by sporozoites and protect against malaria. Needle-free vaccination …
Estrogen, the Peripheral Immune System and Major Depression–A Reproductive Lifespan Perspective
EB Engler-Chiurazzi, WH Chastain… - Frontiers in Behavioral …, 2022 - frontiersin.org
Major depression is a significant medical issue impacting millions of individuals worldwide.
Identifying factors contributing to its manifestation has been a subject of intense investigation …
Identifying factors contributing to its manifestation has been a subject of intense investigation …
The effect of chronic stress on the immunogenicity and immunoprotection of the M6-TT vaccine in female mice
SB Méndez, M Matus-Ortega, RH Miramontes… - Physiology & …, 2023 - Elsevier
Active vaccination is an effective therapeutic option to reduce the reinforcing effects of
opioids. Several studies showed that chronic stress affects the immune system decreasing …
opioids. Several studies showed that chronic stress affects the immune system decreasing …