[HTML][HTML] Delayed graft function in the kidney transplant

A Siedlecki, W Irish, DC Brennan - American journal of transplantation, 2011 - Elsevier
Acute kidney injury occurs with kidney transplantation and too frequently progresses to the
clinical diagnosis of delayed graft function (DGF). Poor kidney function in the first week of …

Recent approaches to targeting canonical NFκB signaling in the early inflammatory response to renal IRI

S Reid, JW Scholey - Journal of the American Society of …, 2021 - journals.lww.com
Ischemia reperfusion injury (IRI) is the most common cause of in-hospital AKI and is
associated with increased morbidity and mortality. IRI is associated with an early phase of …

Protective effect of tea polyphenols on renal ischemia/reperfusion injury via suppressing the activation of TLR4/NF-κB p65 signal pathway

YW Li, Y Zhang, L Zhang, X Li, JB Yu, HT Zhang… - Gene, 2014 - Elsevier
Tea polyphenols (TP) was investigated in rats for its protective effect on renal
ischemia/reperfusion injury (RIRI). Rats were randomized into groups as follows:(I) sham …

Heparanase regulates the M1 polarization of renal macrophages and their crosstalk with renal epithelial tubular cells after ischemia/reperfusion injury

V Masola, G Zaza, G Bellin, L Dall'Olmo… - The FASEB …, 2018 - Wiley Online Library
Heparanase (HPSE) is part of the biologic network triggered by ischemia/reperfusion (I/R)
injury, a complication of renal transplantation and acute kidney injury. During this period, the …

S1 PR 3 is essential for phosphorylated fingolimod to protect astrocytes against oxygen‐glucose deprivation‐induced neuroinflammation via inhibiting TLR 2/4‐NF κB …

YF Dong, RB Guo, J Ji, LL Cao, L Zhang… - Journal of cellular …, 2018 - Wiley Online Library
Fingolimod (FTY 720) is used as an immunosuppressant for multiple sclerosis. Numerous
studies indicated its neuroprotective effects in stroke. However, the mechanism remains to …

[HTML][HTML] Upregulation of TLR4 mRNA expression levels in broiler chickens under acute heat stress

S Huang - Revista Brasileira De Ciência Avícola, 2017 - SciELO Brasil
Toll-like receptors (TLRs) are well-characterized in mice and rats, but little is known on their
role in broiler chickens during acute heat stress (AHS). The aim of the present study was to …

Targeting the sphingosine kinase/sphingosine 1‐phosphate pathway to treat chronic inflammatory kidney diseases

S Schwalm, J Pfeilschifter… - Basic & clinical …, 2014 - Wiley Online Library
Chronic kidney diseases including glomerulonephritis are often accompanied by acute or
chronic inflammation that leads to an increase in extracellular matrix (ECM) production and …

[HTML][HTML] Aquaporin-3 deletion in mice results in renal collecting duct abnormalities and worsens ischemia-reperfusion injury

L Lei, W Wang, Y Jia, L Su, H Zhou, AS Verkman… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Abstract Aquaporin-3 (AQP3), a transporter of water, glycerol and H 2 O 2, is expressed in
basolateral membranes of principal cells in kidney collecting duct. Here, we report that …

Ischaemic and inflammatory injury in renal graft from brain death donation: an update review

A Fung, H Zhao, B Yang, Q Lian, D Ma - Journal of anesthesia, 2016 - Springer
Renal transplantation remains an important therapy in treating renal failure and can be
considered to be a curative treatment. The demand for renal grafts outstrips supply available …

RP105 protects against myocardial ischemia–reperfusion injury via suppressing TLR4 signaling pathways in rat model

X Li, J Yang, J Yang, W Dong, S Li, H Wu… - … and Molecular Pathology, 2016 - Elsevier
Myocardial ischemia–reperfusion (I/R) injury severely impacts the postoperative survival rate
of coronary atherosclerotic heart disease. Radioprotective 105 kDa protein (RP105) is a …