Alternative splicing and related RNA binding proteins in human health and disease
Y Tao, Q Zhang, H Wang, X Yang, H Mu - Signal Transduction and …, 2024 - nature.com
Alternative splicing (AS) serves as a pivotal mechanism in transcriptional regulation,
engendering transcript diversity, and modifications in protein structure and functionality …
engendering transcript diversity, and modifications in protein structure and functionality …
Alternative pre-mRNA splicing in stem cell function and therapeutic potential: A critical review of current evidence
L Cui, Y Zheng, R Xu, Y Lin, J Zheng, P Lin… - International Journal of …, 2024 - Elsevier
Alternative splicing is a crucial regulator in stem cell biology, intricately influencing the
functions of various biological macromolecules, particularly pre-mRNAs and the resultant …
functions of various biological macromolecules, particularly pre-mRNAs and the resultant …
CWF19L2 is Essential for Male Fertility and Spermatogenesis by Regulating Alternative Splicing
S Wang, Y Cai, T Li, Y Wang, Z Bao, R Wang… - Advanced …, 2024 - Wiley Online Library
The progression of spermatogenesis along specific developmental trajectories depends on
the coordinated regulation of pre‐mRNA alternative splicing (AS) at the post‐transcriptional …
the coordinated regulation of pre‐mRNA alternative splicing (AS) at the post‐transcriptional …
DCAF2 regulates the proliferation and differentiation of mouse progenitor spermatogonia by targeting p21 and thymine DNA glycosylase
H Wei, Z Wang, Y Huang, L Gao, W Wang… - Cell …, 2024 - Wiley Online Library
Abstract DDB1‐Cullin‐4‐associated factor‐2 (DCAF2, also known as DTL or CDT2), a
conserved substrate recognition protein of Cullin‐RING E3 ligase 4 (CRL4), recognizes and …
conserved substrate recognition protein of Cullin‐RING E3 ligase 4 (CRL4), recognizes and …
SRSF10 regulates migration of neural progenitor cells and granule cells and affects the formation of dentate gyrus during the development of mouse hippocampus
A Ma, Y Mu, Z Wei, M Sun, J Li, H Jiang, C Zhu, X Chen - Neuroscience, 2024 - Elsevier
Hippocampus is a critical component of the central nervous system. SRSF10 is expressed in
central nervous system and plays important roles in maintaining normal brain functions …
central nervous system and plays important roles in maintaining normal brain functions …
[HTML][HTML] Transmission ratio distortion detection by neutral genetic markers in the Pura Raza Española horse breed
DI Perdomo-González, S Id-Lahoucine, A Molina… - animal, 2023 - Elsevier
Abstract Transmission Ratio Distortion (TRD) is a genetic phenomenon widely demonstrated
in several livestock species, but barely in equine species. The TRD occurs when certain …
in several livestock species, but barely in equine species. The TRD occurs when certain …
RNA splicing as a biomarker and phenotypic driver of meningioma DNA methylation groups
NK Leclair, A Choudury, WC Chen, ST Magill… - Neuro …, 2024 - academic.oup.com
Background Advances in our understanding of the molecular biology of meningiomas have
led to significant gains in the ability to predict patient prognosis and tumor recurrence and to …
led to significant gains in the ability to predict patient prognosis and tumor recurrence and to …
Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice
L Sun, Z Lv, X Chen, R Ye, S Tian, C Wang, X Xie… - Elife, 2024 - elifesciences.org
Spermatogonial stem cells (SSCs) are essential for continuous spermatogenesis and male
fertility. The underlying mechanisms of alternative splicing (AS) in mouse SSCs are still …
fertility. The underlying mechanisms of alternative splicing (AS) in mouse SSCs are still …
SRSF1-mediated alternative splicing of Tial1/Tiar is essential for homing and self-renewal in mouse spermatogonial stem cells
L Sun, Z Lv, X Chen, R Ye, S Tian, C Wang, X Xie… - bioRxiv, 2023 - biorxiv.org
Spermatogonial stem cells (SSCs) are essential for continuous spermatogenesis and male
fertility. The underlying mechanisms of alternative splicing (AS) in mouse SSCs are still …
fertility. The underlying mechanisms of alternative splicing (AS) in mouse SSCs are still …