Osteoarthritis (OA) is a degenerative multifactorial disease with concomitant structural,
inflammatory, and metabolic changes that fluctuate in a temporal and patient-specific …

Mesenchymal stromal cell (MSC) therapies have been pursued for a broad spectrum of
indications but mixed reports on clinical efficacy have given rise to some degree of …

In 1949 Polge, Parks and Smith1 reported on the “chance” discovery of glycerol's
cryoprotective function during their efforts to preserve avian spermatozoa in the frozen state …

There has been a great deal of scientific interest recently generated by the potential
therapeutic applications of adult stem cells in human care but there are several challenges …

Long-term storage of cell stocks insures that cells are available for use whenever needed.
Cryopreservation of cells is the method of choice for preservation of important or rare cell …

Achievements in tissue engineering using mesenchymal stem cells (MSC) demand a
clinically acceptable “off-the-shelf” cell therapy product. Efficacy of cryopreservation of …

Current preservation strategies range from the storage of cells, tissues, and organs for hours
at hypothermic temperatures (from 25° C to 4° C) to extended periods of time (ie, years) at …

Developing effective techniques for the cryopreservation of human adipose-derived adult
stem cells (ASCs) could increase the usefulness of these cells in tissue engineering and …

Antioxidant systems are important defense systems in plants, and studying their response to
environmental stress helps reveal the mechanisms underlying plant stress tolerance. Pollen …

The rapid cold-hardening (RCH) response increases the cold tolerance of insects by
protecting against non-freezing, cold-shock injury. Apoptosis, or programmed cell death …