Bile acids and the gut microbiota: metabolic interactions and impacts on disease
Despite decades of bile acid research, diverse biological roles for bile acids have been
discovered recently due to developments in understanding the human microbiota. As …
discovered recently due to developments in understanding the human microbiota. As …
Gut microbiota in colorectal cancer development and therapy
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
[HTML][HTML] Gut microbiome and health: mechanistic insights
The gut microbiota is now considered as one of the key elements contributing to the
regulation of host health. Virtually all our body sites are colonised by microbes suggesting …
regulation of host health. Virtually all our body sites are colonised by microbes suggesting …
[HTML][HTML] Gut microbiota-derived bile acids in intestinal immunity, inflammation, and tumorigenesis
J Cai, L Sun, FJ Gonzalez - Cell host & microbe, 2022 - cell.com
Inflammatory bowel disease (IBD) and colorectal cancer (CRC) are heterogeneous intestinal
diseases that threaten the health of an increasing number of individuals as their lifestyles …
diseases that threaten the health of an increasing number of individuals as their lifestyles …
Microbial transformations of human bile acids
Bile acids play key roles in gut metabolism, cell signaling, and microbiome composition.
While the liver is responsible for the production of primary bile acids, microbes in the gut …
While the liver is responsible for the production of primary bile acids, microbes in the gut …
Bile acids as modulators of gut microbiota composition and function
AB Larabi, HLP Masson, AJ Bäumler - Gut Microbes, 2023 - Taylor & Francis
Changes in the composition of gut-associated microbial communities are associated with
many human illnesses, but the factors driving dysbiosis remain incompletely understood …
many human illnesses, but the factors driving dysbiosis remain incompletely understood …
The gut microbiome and hypertension
A large body of evidence has emerged in the past decade supporting a role for the gut
microbiome in the regulation of blood pressure. The field has moved from association to …
microbiome in the regulation of blood pressure. The field has moved from association to …
Bile acid metabolism and signaling, the microbiota, and metabolic disease
The diversity, composition, and function of the bacterial community inhabiting the human
gastrointestinal tract contributes to host health through its role in producing energy or …
gastrointestinal tract contributes to host health through its role in producing energy or …
Impact of bacterial metabolites on gut barrier function and host immunity: a focus on bacterial metabolism and its relevance for intestinal inflammation
N Gasaly, P De Vos, MA Hermoso - Frontiers in immunology, 2021 - frontiersin.org
The diverse and dynamic microbial community of the human gastrointestinal tract plays a
vital role in health, with gut microbiota supporting the development and function of the gut …
vital role in health, with gut microbiota supporting the development and function of the gut …
Gut microbiota-derived metabolites as key actors in inflammatory bowel disease
A key role of the gut microbiota in the establishment and maintenance of health, as well as in
the pathogenesis of disease, has been identified over the past two decades. One of the …
the pathogenesis of disease, has been identified over the past two decades. One of the …