Novel research and future prospects of artificial intelligence in cancer diagnosis and treatment

C Zhang, J Xu, R Tang, J Yang, W Wang, X Yu… - Journal of Hematology & …, 2023 - Springer
Research into the potential benefits of artificial intelligence for comprehending the intricate
biology of cancer has grown as a result of the widespread use of deep learning and …

Artificial Intelligence in Oncology: Current Landscape, Challenges, and Future Directions

W Lotter, MJ Hassett, N Schultz, KL Kehl, EM Van Allen… - Cancer Discovery, 2024 - AACR
Artificial intelligence (AI) in oncology is advancing beyond algorithm development to
integration into clinical practice. This review describes the current state of the field, with a …

Machine learning and deep learning for brain tumor MRI image segmentation

MKH Khan, W Guo, J Liu, F Dong, Z Li… - Experimental …, 2023 - journals.sagepub.com
Brain tumors are often fatal. Therefore, accurate brain tumor image segmentation is critical
for the diagnosis, treatment, and monitoring of patients with these tumors. Magnetic …

Deep learning in cancer genomics and histopathology

M Unger, JN Kather - Genome Medicine, 2024 - Springer
Histopathology and genomic profiling are cornerstones of precision oncology and are
routinely obtained for patients with cancer. Traditionally, histopathology slides are manually …

Role of artificial intelligence in haematolymphoid diagnostics

C Syrykh, M van den Brand, JN Kather… - …, 2024 - Wiley Online Library
The advent of digital pathology and the deployment of high‐throughput molecular
techniques are generating an unprecedented mass of data. Thanks to advances in …

Haplotype-resolved assemblies and variant benchmark of a Chinese Quartet

P Jia, L Dong, X Yang, B Wang, SJ Bush, T Wang, J Lin… - Genome Biology, 2023 - Springer
Background Recent state-of-the-art sequencing technologies enable the investigation of
challenging regions in the human genome and expand the scope of variant benchmarking …

Knowledge structure and emerging trends in the application of deep learning in genetics research: A bibliometric analysis [2000–2021]

B Zhang, T Fan - Frontiers in Genetics, 2022 - frontiersin.org
Introduction: Deep learning technology has been widely used in genetic research because
of its characteristics of computability, statistical analysis, and predictability. Herein, we aimed …

AIVariant: a deep learning-based somatic variant detector for highly contaminated tumor samples

H Jeon, J Ahn, B Na, S Hong, L Sael, S Kim… - … & Molecular Medicine, 2023 - nature.com
The detection of somatic DNA variants in tumor samples with low tumor purity or sequencing
depth remains a daunting challenge despite numerous attempts to address this problem. In …

Evaluation of false positive and false negative errors in targeted next generation sequencing

Y Moon, YH Kim, JK Kim, CH Hong, EK Kang, HW Choi… - bioRxiv, 2024 - biorxiv.org
Background: Although next generation sequencing (NGS) has been adopted as an essential
diagnostic tool in various diseases, NGS errors have been the most serious problem in …

ClairS: a deep-learning method for long-read somatic small variant calling

ZX Zheng, J Su, L Chen, YL Lee, TW Lam, R Luo - bioRxiv, 2023 - biorxiv.org
Identifying somatic variants in tumor samples is a crucial task, which is often performed
using statistical methods and heuristic filters applied to short-read data. However, with the …