Osteoarthritis: pathogenic signaling pathways and therapeutic targets

Q Yao, X Wu, C Tao, W Gong, M Chen, M Qu… - Signal transduction and …, 2023 - nature.com
Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Osteoarthritis: pathology, diagnosis, and treatment options

B Abramoff, FE Caldera - Medical Clinics, 2020 - medical.theclinics.com
Osteoarthritis (OA) is endemic throughout the world. An estimated 30.8 million adults in the
United States and 300 million individuals worldwide are living with OA. 1, 2 It is the leading …

2021 EULAR recommendations regarding lifestyle behaviours and work participation to prevent progression of rheumatic and musculoskeletal diseases

JM Gwinnutt, M Wieczorek, A Balanescu… - Annals of the …, 2023 - ard.bmj.com
Objectives A European League Against Rheumatism taskforce was convened to review the
literature and develop recommendations on lifestyle behaviours for rheumatic and …

Role of kinesiophobia on pain, disability and quality of life in people suffering from chronic musculoskeletal pain: a systematic review

A Luque-Suarez, J Martinez-Calderon… - British journal of sports …, 2019 - bjsm.bmj.com
Objective (1) To explore the level of association between kinesiophobia and pain, disability
and quality of life in people with chronic musculoskeletal pain (CMP) detected via cross …

Ageing and osteoarthritis

PK Sacitharan - Biochemistry and cell biology of ageing: part II clinical …, 2019 - Springer
The increase in global lifespan has in turn increased the prevalence of osteoarthritis which
is now the most common type of arthritis. Cartilage tissue located on articular joints erodes …

Exercise for osteoarthritis of the knee: a Cochrane systematic review

M Fransen, S McConnell, AR Harmer… - British journal of sports …, 2015 - bjsm.bmj.com
Objective To determine whether land-based therapeutic exercise is beneficial for people
with knee osteoarthritis (OA) in terms of reduced joint pain or improved physical function and …

Exercise interventions and patient beliefs for people with hip, knee or hip and knee osteoarthritis: a mixed methods review

M Hurley, K Dickson, R Hallett, R Grant… - Cochrane Database …, 2018 - cochranelibrary.com
Background Chronic peripheral joint pain due to osteoarthritis (OA) is extremely prevalent
and a major cause of physical dysfunction and psychosocial distress. Exercise is …

Effective treatment options for musculoskeletal pain in primary care: a systematic overview of current evidence

OO Babatunde, JL Jordan, DA Van der Windt, JC Hill… - PloS one, 2017 - journals.plos.org
Background & aims Musculoskeletal pain, the most common cause of disability globally, is
most frequently managed in primary care. People with musculoskeletal pain in different body …

Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials

GC Machado, CG Maher, PH Ferreira, MB Pinheiro… - bmj, 2015 - bmj.com
Objective To investigate the efficacy and safety of paracetamol (acetaminophen) in the
management of spinal pain and osteoarthritis of the hip or knee. Design Systematic review …

[HTML][HTML] Effects of physical activity in knee and hip osteoarthritis: a systematic umbrella review

VB Kraus, K Sprow, KE Powell, D Buchner… - Medicine and science …, 2019 - ncbi.nlm.nih.gov
Methods. Our primary search encompassed 2011–2/2018 for existing systematic reviews
(SRs), meta-analyses (MAs) and pooled analyses dealing with physical activity including …