Enhancing permeation of drug molecules across the skin via delivery in nanocarriers: novel strategies for effective transdermal applications

YQ Yu, X Yang, XF Wu, YB Fan - Frontiers in bioengineering and …, 2021 - frontiersin.org
The transdermal route of administration provides numerous advantages over conventional
routes ie, oral or injectable for the treatment of different diseases and cosmetics applications …

Topical and transdermal drug delivery: from simple potions to smart technologies

HAE Benson, JE Grice, Y Mohammed… - Current drug …, 2019 - ingentaconnect.com
This overview on skin delivery considers the evolution of the principles of percutaneous
absorption and skin products from ancient times to today. Over the ages, it has been …

Skin permeabilization for transdermal drug delivery: recent advances and future prospects

CM Schoellhammer, D Blankschtein… - Expert opinion on drug …, 2014 - Taylor & Francis
Introduction: Transdermal delivery has potential advantages over other routes of
administration. It could reduce first-pass metabolism associated with oral delivery and is less …

Iontophoretic drug delivery

YN Kalia, A Naik, J Garrison, RH Guy - Advanced drug delivery reviews, 2004 - Elsevier
The composition and architecture of the stratum corneum render it a formidable barrier to the
topical and transdermal administration of therapeutic agents. The physicochemical …

Transdermal drug delivery: overcoming the skin's barrier function

A Naik, YN Kalia, RH Guy - Pharmaceutical science & technology today, 2000 - Elsevier
The skin represents an extraordinary evolutionary feat. Not only does it physically
encapsulate the organism and provide a multifunctional interface between us and our …

Dermal and transdermal drug delivery systems: current and future prospects

MB Brown, GP Martin, SA Jones, FK Akomeah - Drug delivery, 2006 - Taylor & Francis
The protective function of human skin imposes physicochemical limitations to the type of
permeant that can traverse the barrier. For a drug to be delivered passively via the skin it …

Overcoming ocular drug delivery barriers through the use of physical forces

D Huang, YS Chen, ID Rupenthal - Advanced drug delivery reviews, 2018 - Elsevier
Overcoming the physiological barriers in the eye remains a key obstacle in the field of ocular
drug delivery. While ocular barriers naturally have a protective function, they also limit drug …

Getting drugs across biological barriers

R Yang, T Wei, H Goldberg, W Wang… - Advanced …, 2017 - Wiley Online Library
The delivery of drugs to a target site frequently involves crossing biological barriers. The
degree and nature of the impediment to flux, as well as the potential approaches to …

Smart skin‐adhesive patches: from design to biomedical applications

SHD Wong, GR Deen, JS Bates, C Maiti… - Advanced Functional …, 2023 - Wiley Online Library
With the advancement of medical and digital technologies, smart skin adhesive patches
have emerged as a key player for complex medical purposes. In particular, skin adhesive …

Recent advances in transdermal drug delivery

RK Subedi, SY Oh, MK Chun, HK Choi - Archives of Pharmacal Research, 2010 - Springer
Transdermal delivery of pharmacologically active agents has been extensively studied for
the past 40 years. Despite the strong efforts, currently, only about 40 products are in market …