A guide to plasma membrane solute carrier proteins

MD Pizzagalli, A Bensimon… - The FEBS …, 2021 - Wiley Online Library
This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily
of transporter proteins and their roles in human cells. The SLC superfamily currently …

The role of Fe, Zn, and Cu in pregnancy

K Grzeszczak, S Kwiatkowski, D Kosik-Bogacka - Biomolecules, 2020 - mdpi.com
Iron (Fe), copper (Cu), and zinc (Zn) are microelements essential for the proper functioning
of living organisms. These elements participatein many processes, including cellular …

The role of zinc in male fertility

D Allouche-Fitoussi, H Breitbart - International journal of molecular …, 2020 - mdpi.com
Several studies proposed the importance of zinc ion in male fertility. Here, we describe the
properties, roles and cellular mechanisms of action of Zn2+ in spermatozoa, focusing on its …

Regulation of zinc-dependent enzymes by metal carrier proteins

MW Thompson - Biometals, 2022 - Springer
Zn2+ ions are essential in many physiological processes, including enzyme catalysis,
protein structural stabilization, and the regulation of many proteins. The affinities of proteins …

The impact of zinc and zinc homeostasis on the intestinal mucosal barrier and intestinal diseases

Y Wan, B Zhang - Biomolecules, 2022 - mdpi.com
Zinc is an essential trace element for living organisms, and zinc homeostasis is essential for
the maintenance of the normal physiological functions of cells and organisms. The intestine …

Ion channelopathies of the immune system

M Vaeth, S Feske - Current opinion in immunology, 2018 - Elsevier
Ion channels and transporters move ions across membrane barriers and are essential for a
host of cell functions in many organs. They conduct K+, Na+ and Cl−, which are essential for …

Neurobiology of zinc and its role in neurogenesis

V Kumar, A Kumar, K Singh, K Avasthi… - European Journal of …, 2021 - Springer
Abstract Background Zinc (Zn) has a diverse role in many biological processes, such as
growth, immunity, anti-oxidation system, homeostatic, and repairing. It acts as a regulatory …

Roles of zinc in cancers: from altered metabolism to therapeutic applications

M Bendellaa, P Lelièvre, JL Coll… - … Journal of Cancer, 2024 - Wiley Online Library
Zinc (Zn) is a crucial trace element involved in various cellular processes, including
oxidative stress, apoptosis and immune response, contributing to cellular homeostasis …

Growth modulatory role of zinc in prostate cancer and application to cancer therapeutics

PK To, MH Do, JH Cho, C Jung - International journal of molecular …, 2020 - mdpi.com
Zinc is a group IIB heavy metal. It is an important regulator of major cell signaling pathways
in most mammalian cells, functions as an antioxidant and plays a role in maintaining …

Role of zinc supplementation on ischemia/reperfusion injury in various organs

G Akbari - Biological Trace Element Research, 2020 - Springer
Abstract Ischemia-reperfusion (I/R) injury is a serious condition which is associated with
myocardial infarction, stroke, acute kidney injury, trauma, circulatory arrest, sickle cell …