On 12 March 2020, the outbreak of coronavirus disease 2019 (COVID-19) was declared a
pandemic by the World Health Organization. As of 4 August 2020, more than 18 million …

Haemodialysis is a life-saving renal replacement modality for end-stage renal disease, but
this therapy also represents a major challenge to the intravascular innate immune system …

Alopecia areata (AA) is a CD8+ T-cell dependent autoimmune disease of the hair follicle
(HF) in which the collapse of HF immune privilege (IP) plays a key role. Mast cells (MCs) are …

The outbreak of coronavirus disease 2019 (COVID-19) caused by the betacoronavirus
SARS-CoV-2 is now a worldwide challenge for healthcare systems. Although the leading …

Bradykinin is a small active peptide and is considered an inflammatory mediator in several
pathological conditions. Bradykinin exerts its effects by coupling to its receptors, including …

Individuals receiving long-term hemodialysis are at increased risk of developing
cardiovascular disease (CVD). Traditional cardiovascular risk factors do not fully explain the …

Pain caused by the tumor or aromatase inhibitors (AIs) is a disabling symptom in breast
cancer survivors. Their mechanisms are unclear, but pro-algesic and inflammatory …

Background Early dysregulation of local and systemic inflammatory and immune responses
is implicated in the pathogenesis of fibrotic and degenerative complications after anterior …

The significance of developing host-modulating personalized therapies to counteract the
growing threat of antimicrobial resistance is well-recognized because such resistance …

Kinins are bioactive peptides generated in the inflammatory milieu of the tissue
microenvironment, which is involved in cancer progression and inflammatory response …