Molecular and cellular mechanisms for PRRSV pathogenesis and host response to infection
Porcine reproductive and respiratory syndrome virus (PRRSV) has caused tremendous
amounts of economic losses to the swine industry for more than three decades, but its …
amounts of economic losses to the swine industry for more than three decades, but its …
Network pharmacology and molecular docking analyses on Lianhua Qingwen capsule indicate Akt1 is a potential target to treat and prevent COVID‐19
Abstract Objectives Coronavirus disease 2019 (COVID‐19) is rapidly spreading worldwide.
Lianhua Qingwen capsule (LQC) has shown therapeutic effects in patients with COVID‐19 …
Lianhua Qingwen capsule (LQC) has shown therapeutic effects in patients with COVID‐19 …
[PDF][PDF] Interference of interleukin-1β mediated by lentivirus promotes functional recovery of spinal cord contusion injury in rats via the PI3K/AKT signaling pathway
Y Wang, X Hu, Q Li, L Zhang, Q Xia, N Liang, W Liu… - 2020 - scholar.archive.org
Background: Spinal cord contusion (SCC) results in a series of pathophysiologic
consequences such as edema, apoptosis, and in ammation. However, in ammation may …
consequences such as edema, apoptosis, and in ammation. However, in ammation may …
Deciphering suppressive effects of Lianhua Qingwen Capsule on COVID-19 and synergistic effects of its major botanical drug pairs
C Yuanyuan, C Zhang, W Ning, F Yibin - Chinese Journal of Natural …, 2023 - Elsevier
The COVID-19 pandemic has resulted in excess deaths worldwide. Conventional antiviral
medicines have been used to relieve the symptoms, with limited therapeutic effect. In …
medicines have been used to relieve the symptoms, with limited therapeutic effect. In …
A practical strategy for exploring the pharmacological mechanism of luteolin against COVID-19/asthma comorbidity: findings of system pharmacology and …
YZ Xie, CW Peng, ZQ Su, HT Huang, XH Liu… - Frontiers in …, 2022 - frontiersin.org
Asthma patients may increase their susceptibility to SARS-CoV-2 infection and the poor
prognosis of coronavirus disease 2019 (COVID-19). However, anti-COVID-19/asthma …
prognosis of coronavirus disease 2019 (COVID-19). However, anti-COVID-19/asthma …
Network pharmacology and bioinformatics analysis identifies potential therapeutic targets of Naringenin against COVID-19/LUSC
W Wu, X Jiao, W Song, P Wu, P Xiao… - Frontiers in …, 2023 - frontiersin.org
Background Coronavirus disease 2019 (COVID‐19) is a highly contagious respiratory
disease that has posed a serious threat to people's daily lives and caused an …
disease that has posed a serious threat to people's daily lives and caused an …
Identifying the molecular targets and mechanisms of xuebijing injection for the treatment of COVID-19 via network pharmacology and molecular docking
Z Tianyu, G Liying - Bioengineered, 2021 - Taylor & Francis
Xuebijing Injection have been found to improve the clinical symptoms of COVID-19 and
alleviate disease severity, but the mechanisms are currently unclear. This study aimed to …
alleviate disease severity, but the mechanisms are currently unclear. This study aimed to …
A genome-wide association study of fetal response to type 2 porcine reproductive and respiratory syndrome virus challenge
T Yang, J Wilkinson, Z Wang, A Ladinig, J Harding… - Scientific reports, 2016 - nature.com
Control of porcine reproductive and respiratory syndrome (PRRS) is economically important
for the swine industry worldwide. As current PRRS vaccines do not completely protect …
for the swine industry worldwide. As current PRRS vaccines do not completely protect …
PDCD4 restricts PRRSV replication in an eIF4A-dependent manner and is antagonized by the viral nonstructural protein 9
R Wei, X Zhang, X Wang, L Li, Y Fu, Y Chen… - Journal of …, 2024 - Am Soc Microbiol
As obligate parasites, viruses have evolved multiple strategies to evade the host immune
defense. Manipulation of the host proteasome system to degrade specific detrimental factors …
defense. Manipulation of the host proteasome system to degrade specific detrimental factors …
Role of phosphatidylinositol-3-kinase (PI3K) and the mammalian target of rapamycin (mTOR) signalling pathways in porcine reproductive and respiratory syndrome …
S Pujhari, M Kryworuchko, AN Zakhartchouk - Virus research, 2014 - Elsevier
Abstract Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is a positive
sense, single-stranded RNA genome virus that has become a major infection in swine …
sense, single-stranded RNA genome virus that has become a major infection in swine …