[HTML][HTML] The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

[HTML][HTML] Exploring the emerging role of the microbiome in cancer immunotherapy

J Fessler, V Matson, TF Gajewski - Journal for immunotherapy of cancer, 2019 - Springer
The activity of the commensal microbiota significantly impacts human health and has been
linked to the development of many diseases, including cancer. Gnotobiotic animal models …

The gut metabolite indole-3 propionate promotes nerve regeneration and repair

E Serger, L Luengo-Gutierrez, JS Chadwick, G Kong… - Nature, 2022 - nature.com
The regenerative potential of mammalian peripheral nervous system neurons after injury is
critically limited by their slow axonal regenerative rate. Regenerative ability is influenced by …

PICRUSt2 for prediction of metagenome functions

GM Douglas, VJ Maffei, JR Zaneveld, SN Yurgel… - Nature …, 2020 - nature.com
To the Editor—One limitation of microbial community marker-gene sequencing is that it does
not provide information about the functional composition of sampled communities …

Microbiota from young mice counteracts selective age-associated behavioral deficits

M Boehme, KE Guzzetta, TFS Bastiaanssen… - Nature Aging, 2021 - nature.com
The gut microbiota is increasingly recognized as an important regulator of host immunity and
brain health. The aging process yields dramatic alterations in the microbiota, which is linked …

PICRUSt2: An improved and extensible approach for metagenome inference

GM Douglas, VJ Maffei, J Zaneveld, SN Yurgel… - BioRxiv, 2019 - biorxiv.org
One major limitation of microbial community marker gene sequencing is that it does not
provide direct information on the functional composition of sampled communities. Here, we …

[HTML][HTML] Tax4Fun2: prediction of habitat-specific functional profiles and functional redundancy based on 16S rRNA gene sequences

F Wemheuer, JA Taylor, R Daniel, E Johnston… - Environmental …, 2020 - Springer
Abstract Background Sequencing of 16S rRNA genes has become a powerful technique to
study microbial communities and their responses towards changing environmental …

[HTML][HTML] Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease

FJ Ryan, AM Ahern, RS Fitzgerald… - Nature …, 2020 - nature.com
Studies of inflammatory bowel disease (IBD) have been inconclusive in relating microbiota
with distribution of inflammation. We report microbiota, host transcriptomics, epigenomics …

Correlation and association analyses in microbiome study integrating multiomics in health and disease

Y Xia - Progress in molecular biology and translational …, 2020 - Elsevier
Correlation and association analyses are one of the most widely used statistical methods in
research fields, including microbiome and integrative multiomics studies. Correlation and …

Evaluating the information content of shallow shotgun metagenomics

B Hillmann, GA Al-Ghalith, RR Shields-Cutler, Q Zhu… - Msystems, 2018 - Am Soc Microbiol
Although microbial communities are associated with human, environmental, plant, and
animal health, there exists no cost-effective method for precisely characterizing species and …