The neurotransmitters GABA and glycine mediate fast synaptic inhibition by activating ligand-
gated chloride channels—namely, type A GABA (GABAA) and glycine receptors. Both types …

Super-resolution microscopy (SRM) methods have allowed scientists to exceed the
diffraction limit of light, enabling the discovery and investigation of cellular structures at the …

Glycine receptors (GlyRs) are pentameric,'Cys-loop'receptors that form chloride-permeable
channels and mediate fast inhibitory signalling throughout the central nervous system,. In …

Photoswitchable fluorescent probes are central to localization-based super-resolution
microscopy. Among these probes, fluorescent proteins are appealing because they are …

The strength of synaptic transmission is controlled by the number and activity of
neurotransmitter receptors. However, little is known about absolute numbers and densities …

Single-molecule localization microscopy (SMLM) generates super-resolution images by
serially detecting individual fluorescent molecules. The power of SMLM, however, goes …

Glycine is a non-essential amino acid with many functions and effects. Glycine can bind to
specific receptors and transporters that are expressed in many types of cells throughout an …

Stochastic optical reconstruction microscopy (STORM) and stimulated emission depletion
(STED) microscopy are two super‐resolution optical microscopy approaches that have …

The recent 2014 Nobel Prize in chemistry honored an era of discoveries and technical
advancements in the field of super‐resolution microscopy. However, the applications of …

Abstract Glycine Receptors (GlyRs) provide inhibitory neuronal input in the spinal cord and
brainstem, which is critical for muscle coordination and sensory perception. Synaptic GlyRs …