Antioxidant Hydrogels: Antioxidant Mechanisms, Design Strategies, and Applications in the Treatment of Oxidative Stress‐Related Diseases

B Hu, Y Ouyang, T Zhao, Z Wang, Q Yan… - Advanced …, 2024 - Wiley Online Library
Oxidative stress is a biochemical process that disrupts the redox balance due to an excess
of oxidized substances within the cell. Oxidative stress is closely associated with a multitude …

Hybrid nanoparticle–hydrogel systems for drug delivery depots and other biomedical applications

W Choi, DS Kohane - ACS nano, 2024 - ACS Publications
Hydrogel-based depots typically tend to remain where injected and have excellent
biocompatibility but are relatively poor at controlling drug release. Nanoparticles (NPs) …

Engineered cyclodextrin-based supramolecular hydrogels for biomedical applications

Y Zhao, Z Zheng, CY Yu, H Wei - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Cyclodextrin (CD)-based supramolecular hydrogels are polymer network systems with the
ability to rapidly form reversible three-dimensional porous structures through multiple cross …

Advancements in hydrogel-based drug delivery systems for the treatment of inflammatory bowel disease: a review

Y Liu, J Huang, S Li, Z Li, C Chen, G Qu, K Chen… - Biomaterials …, 2024 - pubs.rsc.org
Inflammatory bowel disease (IBD) is a chronic disorder that affects millions of individuals
worldwide. However, current drug therapies for IBD are plagued by significant side effects …

[HTML][HTML] Dynamically crosslinked ECM-like hydrogels loaded with ROS-responsive drug nanoparticles for treating inflammation in myocardial infarction and stroke

Z Wang, C Hu, W Zhang, W Liu, S He, Y Liu… - Composites Part B …, 2024 - Elsevier
Following a myocardial infarction (MI) or stroke, the excessive generation of reactive oxygen
species (ROS) within a brief timeframe may induce a pronounced inflammatory reaction …

Reactive oxygen species (ROS)-responsive biomaterials for treating myocardial ischemia-reperfusion injury

Y Zhang, M Jiang, T Wang - Frontiers in Bioengineering and …, 2024 - frontiersin.org
Myocardial ischemia-reperfusion injury (MIRI) is a critical issue that arises when restoring
blood flow after an ischemic event in the heart. Excessive reactive oxygen species (ROS) …

Unlocking the potential of hybrid nanocomposite hydrogels: design, mechanical properties and biomedical performances

A Li, J Nicolas, S Mura - Advanced Functional Materials, 2024 - Wiley Online Library
Hybrid nanocomposite hydrogels consist of the homogeneous incorporation of nano‐objects
in a hydrogel matrix. The latter, whether made of natural or synthetic materials, possesses a …

[HTML][HTML] Temperature-Regulated Synthesis of Hyaluronic Acid-Interpenetrated Polyacrylamide/Poly (Acrylic Acid Sodium Salt) Semi-Interpenetrated Polymer Network …

N Özcan, N Orakdogen - Gels, 2024 - mdpi.com
An alternative synthetic pathway was proposed for the optimization of synthesis to find a
better correlation between the swelling and elasticity of hyaluronic acid-interpenetrated gels …

[HTML][HTML] Targeting Reactive Oxygen Species for Diagnosis of Various Diseases

MY Lee, D Lee, D Choi, KS Kim, PM Kang - Journal of Functional …, 2024 - mdpi.com
Reactive oxygen species (ROS) are generated predominantly during cellular respiration and
play a significant role in signaling within the cell and between cells. However, excessive …

Hyaluronic acid-conjugated methotrexate and 5-fluorouracil for targeted drug delivery

W Shao, Y Yang, W Shen, L Ren, P Zhu - International Journal of …, 2024 - Elsevier
The delivery of chemotherapeutical drugs via nanomaterials has become a focus of
pharmaceutical research over several decades due to improved drug delivery to cancer …