The poor outcome of patients with non-surgically removable advanced hepatocellular
carcinoma (HCC), the most frequent type of primary liver cancer, is mainly due to the high …

The serine/threonine kinase glycogen synthase kinase-3 (GSK-3) was initially identified
because of its key role in the regulation of glycogen synthesis. However, it is now well …

Integrin β (ITGB) superfamily members have been reported to play important roles in
multiple biological functions in various cancers. However, the prognostic and oncologic …

Hepatocellular carcinoma (HCC) is one of the common and fatal malignancies, which is a
significant global health problem. The clinical applicability of traditional surgery and other …

Approximately 90% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC).
PDAC is the fourth leading cause of cancer death world-wide. Therapies for PDAC are …

S100 calcium‐binding protein A (S100A) family members regulate multiple biological
functions related to pancreatic cancer (PC) progression and metastasis. However, the …

Background Microvascular invasion (MVI) is a significant predictive factor for early
recurrence, metastasis, and poor prognosis of hepatocellular carcinoma. The aim of the …

Acquired resistance of hepatocellular carcinoma (HCC) to sorafenib (SFB) is the main
reason for the failure of SFB treatment of the cancer. Abnormal activation of the …

Background: Hepatocellular carcinoma (HCC) is a highly malignant tumor with high
incidence and mortality rates. Aging-related genes are closely related to the occurrence and …

Background It is widely considered that pancreatic cancer (PC) is an immunosuppressive
cancer. Immune-based therapies remain promising therapeutic strategies for PC …