Cytokines network in primary membranous nephropathy

Q Zhao, H Dai, Y Hu, H Jiang, Z Feng, W Liu… - International …, 2022 - Elsevier
There have been extensive studies on the immunological mechanism of primary
membranous nephropathy (PMN). Autoantibodies, being the end product of humoral auto …

[HTML][HTML] The ameliorative effect of mahuang fuzi and shenzhuo decoction on membranous nephropathy of rodent model is associated with autophagy and wnt/β …

Y Gao, H Dai, N Zhang, H Jiang, Z Zhang… - Frontiers in …, 2022 - frontiersin.org
The increased incidence of membranous nephropathy (MN) has made it the most common
pathological type of primary nephrotic syndrome in adults in China. According to the theory …

Potential molecular mechanisms of ephedra herb in the treatment of nephrotic syndrome based on network pharmacology and molecular docking

T Yao, Q Wang, S Han, Y Lu, Y Xu… - BioMed Research …, 2022 - Wiley Online Library
Objective. To explore the possible mechanisms of Ephedra herb (EH) in the treatment of
nephrotic syndrome (NS) by using network pharmacology and molecular docking in this …

[HTML][HTML] Traditional Chinese medicine for idiopathic membranous nephropathy: A systematic review and meta-analysis

W Shan, H Guan, H Gu, R Wang, X Huang, P Li, Y Xie… - Heliyon, 2024 - cell.com
Background Idiopathic membranous nephropathy (IMN) is a rare autoimmune disorder that
causes nephrotic syndromes in adults. Conventional immunosuppressive therapies often …

[HTML][HTML] Level of interleukin-35 in patients with idiopathic membranous nephropathy and its predictive value for remission time

N Zhang, H Dai, X Dong, W Liu, H Jiang… - Frontiers in …, 2022 - frontiersin.org
Objective As a member of interleukin-12 family, interleukin-35 (IL-35) plays an important
regulatory role in immune response. The relationship between IL-35 and idiopathic …

Efficacy and safety of Mahuang Fuzi and Shenzhuo Decoction for treatment of primary membranous nephropathy: a multicenter prospective trial

N Zhang, H Jiang, H Dai, S Huang, Q Zhao… - Renal …, 2024 - Taylor & Francis
Background This study aims to undertake a comprehensive assessment of the effectiveness
and safety profile of Mahuang Fuzi and Shenzhuo Decoction (MFSD) in the management of …

[HTML][HTML] Activation of the IL-6/STAT3 pathway contributes to the pathogenesis of membranous nephropathy and is a target for Mahuang Fuzi and Shenzhuo Decoction …

Q Zhao, H Dai, H Jiang, N Zhang, F Hou… - Biomedicine & …, 2024 - Elsevier
Background Primary membranous nephropathy (PMN) is an autoimmune glomerular
disease. IL-6 is a potential therapeutic target for PMN. Previous clinical studies have …

[HTML][HTML] Identification of molecular mechanism and key biomarkers in membranous nephropathy by bioinformatics analysis

Z Dong, Y Geng, P Zhang, J Tang, Z Cao… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Objectives: Membranous nephropathy (MN) is an autoimmune nephropathy. The incidence
of MN is increasing gradually in recent years. Previous studies focused on antibody …

[HTML][HTML] Traditional Chinese Medicine in Treating Primary Podocytosis: From Fundamental Science to Clinical Research

L Lin, E Tian, J Ren, Z Wu, J Deng… - Frontiers in Pharmacology, 2022 - frontiersin.org
Podocytes form a key component of the glomerular filtration barrier. Damage to podocytes is
referred to as “podocyte disease.” There are many causes of podocyte injury, including …

Comparative pharmacokinetic studies of Ephedra herba in common cold and nephrotic syndrome rat models

Y Cao, N Zhou, T Liu, J Zhang, Y Wang… - Journal of …, 2023 - Wiley Online Library
Ephedra herba is a conventional Chinese medicine to treat cold, fever, asthma, edema, and
lung diseases in the clinic. At present, most pharmacokinetic studies focus on the …