Calcific aortic stenosis
BR Lindman, MA Clavel, P Mathieu, B Iung… - Nature reviews Disease …, 2016 - nature.com
Calcific aortic stenosis (AS) is the most prevalent heart valve disorder in developed
countries. It is characterized by progressive fibro-calcific remodelling and thickening of the …
countries. It is characterized by progressive fibro-calcific remodelling and thickening of the …
Calcification in aortic stenosis: the skeleton key
TA Pawade, DE Newby, MR Dweck - Journal of the American College of …, 2015 - jacc.org
Aortic stenosis is a common, potentially fatal condition that is set to become an increasing
public health burden. Once symptoms develop, there is an inexorable deterioration with a …
public health burden. Once symptoms develop, there is an inexorable deterioration with a …
Lipoprotein (a) and oxidized phospholipids promote valve calcification in patients with aortic stenosis
Abstract Background: Lipoprotein (a)[Lp (a)], a major carrier of oxidized phospholipids
(OxPL), is associated with an increased incidence of aortic stenosis (AS). However, it …
(OxPL), is associated with an increased incidence of aortic stenosis (AS). However, it …
Inflammation and its resolution as determinants of acute coronary syndromes
Inflammation contributes to many of the characteristics of plaques implicated in the
pathogenesis of acute coronary syndromes. Moreover, inflammatory pathways not only …
pathogenesis of acute coronary syndromes. Moreover, inflammatory pathways not only …
Effect of denosumab or alendronic acid on the progression of aortic stenosis: a double-blind randomized controlled trial
TA Pawade, MK Doris, R Bing, AC White, L Forsyth… - Circulation, 2021 - Am Heart Assoc
Background: Valvular calcification is central to the pathogenesis and progression of aortic
stenosis, with preclinical and observational studies suggesting that bone turnover and …
stenosis, with preclinical and observational studies suggesting that bone turnover and …
Calcification in atherosclerotic plaque vulnerability: friend or foe?
X Shi, J Gao, Q Lv, H Cai, F Wang, R Ye… - Frontiers in physiology, 2020 - frontiersin.org
Calcification is a clinical marker of atherosclerosis. This review focuses on recent findings on
the association between calcification and plaque vulnerability. Calcified plaques have …
the association between calcification and plaque vulnerability. Calcified plaques have …
Calcific aortic valve stenosis: hard disease in the heart: a biomolecular approach towards diagnosis and treatment
Calcific aortic valve stenosis (CAVS) is common in the ageing population and set to become
an increasing economic and health burden. Once present, it inevitably progresses and has a …
an increasing economic and health burden. Once present, it inevitably progresses and has a …
Coronary 18F-Sodium Fluoride Uptake Predicts Outcomes in Patients With Coronary Artery Disease
Background Reliable methods for predicting myocardial infarction in patients with
established coronary artery disease are lacking. Coronary 18F-sodium fluoride (18F-NaF) …
established coronary artery disease are lacking. Coronary 18F-sodium fluoride (18F-NaF) …
Cardiac imaging for assessing low-gradient severe aortic stenosis
Up to 40% of patients with aortic stenosis (AS) harbor discordant Doppler-
echocardiographic findings, the most common of which is the presence of a small aortic …
echocardiographic findings, the most common of which is the presence of a small aortic …
Medial arterial calcification: an overlooked player in peripheral arterial disease
CY Ho, CM Shanahan - Arteriosclerosis, thrombosis, and vascular …, 2016 - Am Heart Assoc
Peripheral arterial disease (PAD) is a global health issue that is becoming more prevalent in
an aging world population. Diabetes mellitus and chronic kidney disease are also on the …
an aging world population. Diabetes mellitus and chronic kidney disease are also on the …