Intracerebral haemorrhage expansion: definitions, predictors, and prevention

A Morotti, G Boulouis, D Dowlatshahi, Q Li… - The Lancet …, 2023 - thelancet.com
Haematoma expansion affects a fifth of patients within 24 h of the onset of acute
intracerebral haemorrhage and is associated with death and disability, which makes it an …

Pathophysiology, management, and therapeutics in subarachnoid hemorrhage and delayed cerebral ischemia: an overview

HW Sanicola, CE Stewart, P Luther, K Yabut… - Pathophysiology, 2023 - mdpi.com
Subarachnoid hemorrhage (SAH) is a type of hemorrhagic stroke resulting from the rupture
of an arterial vessel within the brain. Unlike other stroke types, SAH affects both young …

Intensive ambulance-delivered blood-pressure reduction in hyperacute stroke

G Li, Y Lin, J Yang, CS Anderson, C Chen… - … England Journal of …, 2024 - Mass Medical Soc
Background Treatment of acute stroke, before a distinction can be made between ischemic
and hemorrhagic types, is challenging. Whether very early blood-pressure control in the …

Therapies for delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage

VA Shah, LF Gonzalez, JI Suarez - Neurocritical care, 2023 - Springer
Delayed cerebral ischemia (DCI) is one of the most important complications of subarachnoid
hemorrhage. Despite lack of prospective evidence, medical rescue interventions for DCI …

Inhibition of GPR17/ID2 Axis Improve Remyelination and Cognitive Recovery after SAH by Mediating OPC Differentiation in Rat Model

Y Wang, A Jiang, J Yan, D Wen, N Gu, Z Li… - Translational Stroke …, 2023 - Springer
Myelin sheath injury contributes to cognitive deficits following subarachnoid hemorrhage
(SAH). G protein-coupled receptor 17 (GPR17), a membrane receptor, negatively regulates …

Update on the INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4): progress and baseline features in 2053 …

C Chen, Y Lin, F Liu, X Chen, L Billot, Q Li, Y Guo… - Trials, 2023 - Springer
Background and aims Uncertainty persists over the effects of blood pressure (BP) lowering
in acute stroke. The INTEnsive ambulance-delivered blood pressure Reduction in hyper …

Association between baseline pulse pressure and hospital mortality in non-traumatic subarachnoid hemorrhage patients: a retrospective cohort study

J Liu, S Wang, L Ji, X Wang, H Zhao - Frontiers in Neurology, 2023 - frontiersin.org
Background and purpose Previous studies have described an association between pulse
pressure (PP) level and mortality in stroke patients. Evidence of associations between PP …

The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: a safety study

G Tan, AL Huguenard, KM Donovan, P Demarest, X Liu… - medRxiv, 2024 - medrxiv.org
Structured Abstract Introduction Subarachnoid hemorrhage (SAH) is characterized by
intense central inflammation, leading to substantial post-hemorrhagic complications such as …

Intraoperative arterial pressure and delayed cerebral ischemia in patients with aneurysmal subarachnoid hemorrhage after surgical clipping: A retrospective cohort …

J Wang, R Li, S Li, T Ma, X Zhang, Y Ren… - Frontiers in …, 2023 - frontiersin.org
Background Delayed cerebral ischemia (DCI) is the major predictor of poor outcomes in
patients with aSAH. Previous studies have attempted to assess the relationship between …

Effects of an Early Intensive Blood Pressure–lowering Strategy Using Remifentanil and Dexmedetomidine in Patients with Spontaneous Intracerebral Hemorrhage: A …

R Dong, F Li, B Li, Q Chen, X Huang, J Zhang… - …, 2024 - pubs.asahq.org
Background Although it has been established that elevated blood pressure and its variability
worsen outcomes in spontaneous intracerebral hemorrhage, antihypertensives use during …