A complex framework of interacting partners including genetic, proteomic, and metabolic
networks that cooperate to mediate specific functional phenotypes drives human biological …

Ovarian cancer (OC) is a common cause of cancer death among women worldwide, so there
is a pressing need to identify factors influencing OC mortality. Much OC patient clinical data …

In line with the advances in high-throughput technologies, multiple omic datasets have
accumulated to study biological systems and diseases coherently. No single omics data type …

Motivation The reconstruction of small key regulatory networks that explain the differences in
the development of cell (sub) types from single-cell RNA sequencing is a yet unresolved …

A significant challenge in our understanding of biological systems is the high number of
genes with unknown function in many genomes. The fungal genus Aspergillus contains …

Deciphering the variations in the protein interactome is required to reach a systems-level
understanding of tumorigenesis. To accomplish this task, we have considered the clinical …

Background Network-based analysis of gene expression through co-expression networks
can be used to investigate modular relationships occurring between genes performing …

Purpose Steroid-induced osteonecrosis of the femoral head (SONFH) is a refractory
orthopaedic hip joint disease that occurs in young-and middle-aged people. Previous …

Ovarian cancer is a common and, yet, one of the most deadly human cancers due to its
insidious onset and the current lack of robust early diagnostic tests. Tumors are complex …

Background Genomic initiatives such as The Cancer Genome Atlas (TCGA) contain data
from-omics profiling of thousands of tumor samples, which may be used to decipher cancer …