Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. One of the
fundamental processes driving the initiation and progression of CRC is the accumulation of …

Rapidly growing malignant tumors frequently encounter hypoxia and nutrient (eg, glucose)
deprivation, which occurs because of insufficient blood supply. This results in necrotic cell …

Toll‐like receptors (TLRs), a critical family of pattern recognition receptors (PRRs), are
responsible for the innate immune responses via signalling pathways to provide effective …

The innate immune pathway is receiving increasing attention in cancer therapy. This
pathway is ubiquitous across various cell types, not only in innate immune cells but also in …

Regulation of microRNA (miRNA) expression has been extensively studied with respect to
colorectal cancer (CRC), since CRC is one of the leading causes of cancer mortality …

Early-life antibiotic exposure perturbs the intestinal microbiota and accelerates type 1
diabetes (T1D) development in the NOD mouse model. Here, we found that maternal cecal …

Background KRAS mutations in codons 12 and 13 are established predictive biomarkers for
anti-EGFR therapy in colorectal cancer. Previous studies suggest that KRAS codon 61 and …

Staphylococcus epidermidis (S. epidermidis) plays a critical role in modulating cutaneous
inflammatory responses in skin. Although S. epidermidis has been shown to co-colonize …

Human Cytomegalovirus (HCMV) encodes multiple microRNAs (miRNAs) whose functions
are just beginning to be uncovered. Using in silico approaches, we identified the Toll-Like …

Background Growing evidence indicates that miR-200c is involved in carcinogenesis and
tumor progression in non-small-cell lung cancer (NSCLC). However, its precise biological …