Graphene oxide for nonlinear integrated photonics

Y Zhang, J Wu, L Jia, Y Qu, Y Yang… - Laser & Photonics …, 2023 - Wiley Online Library
Integrated photonic devices operating via optical nonlinearities offer a powerful solution for
all‐optical information processing, yielding processing speeds that are well beyond that of …

Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications

R Datta, TM Heaster, JT Sharick… - … of biomedical optics, 2020 - spiedigitallibrary.org
Significance: Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique to
distinguish the unique molecular environment of fluorophores. FLIM measures the time a …

Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis

M Papanicolaou, AL Parker, M Yam, EC Filipe… - Nature …, 2022 - nature.com
The tumour stroma, and in particular the extracellular matrix (ECM), is a salient feature of
solid tumours that plays a crucial role in shaping their progression. Many desmoplastic …

Virtual formalin-fixed and paraffin-embedded staining of fresh brain tissue via stimulated Raman CycleGAN model

Z Liu, L Chen, H Cheng, J Ao, J Xiong, X Liu… - Science …, 2024 - science.org
Intraoperative histology is essential for surgical guidance and decision-making. However,
frozen-sectioned hematoxylin and eosin (H&E) staining suffers from degraded accuracy …

Collagen: quantification, biomechanics and role of minor subtypes in cartilage

BJ Bielajew, JC Hu, KA Athanasiou - Nature Reviews Materials, 2020 - nature.com
Collagen is a ubiquitous biomaterial in vertebrate animals. Although each of its 28 subtypes
contributes to the functions of many different tissues in the body, most studies on collagen or …

Quantitative phase imaging based on holography: trends and new perspectives

Z Huang, L Cao - Light: Science & Applications, 2024 - nature.com
Abstract In 1948, Dennis Gabor proposed the concept of holography, providing a pioneering
solution to a quantitative description of the optical wavefront. After 75 years of development …

Autonomous self-healing organic crystals for nonlinear optics

S Mondal, P Tanari, S Roy, S Bhunia… - Nature …, 2023 - nature.com
Non-centrosymmetric molecular crystals have a plethora of applications, such as
piezoelectric transducers, energy storage and nonlinear optical materials owing to their …

Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC

E Boslem, S Reibe, R Carlessi, B Smeuninx… - Science …, 2023 - science.org
The incidence of hepatocellular carcinoma (HCC) is rapidly rising largely because of
increased obesity leading to nonalcoholic steatohepatitis (NASH), a known HCC risk factor …

Ultrabright and fluorogenic probes for multicolor imaging and tracking of lipid droplets in cells and tissues

M Collot, TK Fam, P Ashokkumar… - Journal of the …, 2018 - ACS Publications
Lipid droplets (LDs) are intracellular lipid-rich organelles that regulate the storage of neutral
lipids and were recently found to be involved in many physiological processes, metabolic …

Predicting postoperative peritoneal metastasis in gastric cancer with serosal invasion using a collagen nomogram

D Chen, Z Liu, W Liu, M Fu, W Jiang, S Xu… - Nature …, 2021 - nature.com
Accurate prediction of peritoneal metastasis for gastric cancer (GC) with serosal invasion is
crucial in clinic. The presence of collagen in the tumour microenvironment affects the …