[HTML][HTML] Decoding the regulatory roles of non-coding RNAs in cellular metabolism and disease
Y Zong, X Wang, B Cui, X Xiong, A Wu, C Lin, Y Zhang - Molecular Therapy, 2023 - cell.com
Non-coding RNAs, including long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and
circular RNAs (circRNAs), are being studied extensively in a variety of fields. Their roles in …
circular RNAs (circRNAs), are being studied extensively in a variety of fields. Their roles in …
[HTML][HTML] Dissecting flux balances to measure energetic costs in cell biology: Techniques and challenges
Life is a nonequilibrium phenomenon: Metabolism provides a continuous supply of energy
that drives nearly all cellular processes. However, very little is known about how much …
that drives nearly all cellular processes. However, very little is known about how much …
Oxamyl exerts developmental toxic effects in zebrafish by disrupting the mitochondrial electron transport chain and modulating PI3K/Akt and p38 Mapk signaling
Oxamyl, a carbamate insecticide, is mainly used to control nematodes in the agricultural
field. Although oxamyl is a widely used insecticide that is associated with ecological …
field. Although oxamyl is a widely used insecticide that is associated with ecological …
Metabolic plasticity sustains the robustness of Caenorhabditis elegans embryogenesis
S Chen, X Su, J Zhu, L Xiao, Y Cong, L Yang, Z Du… - EMBO …, 2023 - embopress.org
Embryogenesis is highly dependent on maternally loaded materials, particularly those used
for energy production. Different environmental conditions and genetic backgrounds shape …
for energy production. Different environmental conditions and genetic backgrounds shape …
Resource allocation in mammalian systems
HM Baghdassarian, NE Lewis - Biotechnology Advances, 2024 - Elsevier
Cells execute biological functions to support phenotypes such as growth, migration, and
secretion. Complementarily, each function of a cell has resource costs that constrain …
secretion. Complementarily, each function of a cell has resource costs that constrain …
[HTML][HTML] Engineering themes in plant forms and functions
R Ohlendorf, NYH Tan… - Annual Review of Plant …, 2023 - annualreviews.org
Living structures constantly interact with the biotic and abiotic environment by sensing and
responding via specialized functional parts. In other words, biological bodies embody highly …
responding via specialized functional parts. In other words, biological bodies embody highly …
Uncovering underlying physical principles and driving forces of cell differentiation and reprogramming from single-cell transcriptomics
L Zhu, S Yang, K Zhang, H Wang, X Fang… - Proceedings of the …, 2024 - pnas.org
Recent advances in single-cell sequencing technology have revolutionized our ability to
acquire whole transcriptome data. However, uncovering the underlying transcriptional …
acquire whole transcriptome data. However, uncovering the underlying transcriptional …
Spatial patterning of energy metabolism during tissue morphogenesis
Biophysical signaling organizes forces to drive tissue morphogenesis, a process co-opted
during disease progression. The systematic buildup of forces at the tissue scale is …
during disease progression. The systematic buildup of forces at the tissue scale is …
[HTML][HTML] Energetic demands regulate sleep-wake rhythm circuit development
AR Poe, L Zhu, SH Tang, E Valencia, MS Kayser - Elife, 2024 - elifesciences.org
Sleep and feeding patterns lack strong daily rhythms during early life. As diurnal animals
mature, feeding is consolidated to the day and sleep to the night. In Drosophila, circadian …
mature, feeding is consolidated to the day and sleep to the night. In Drosophila, circadian …
[HTML][HTML] Glucose promoting the early embryonic development by increasing the lipid synthesis at 2-cell stage
M Wang, J Xue, C Li, L Qi, L Nie, Z Xue - Frontiers in Cell and …, 2023 - frontiersin.org
The optimization of culture conditions is one of the main strategies to improve the embryo
development competence in in vitro fertilization (IVF). Glucose is an important carbon source …
development competence in in vitro fertilization (IVF). Glucose is an important carbon source …