Microfluidics for drug development: from synthesis to evaluation
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …
delivery, and drug evaluation. Compared with conventional drug development procedures …
Evolution of biochip technology: A review from lab-on-a-chip to organ-on-a-chip
N Azizipour, R Avazpour, DH Rosenzweig, M Sawan… - Micromachines, 2020 - mdpi.com
Following the advancements in microfluidics and lab-on-a-chip (LOC) technologies, a novel
biomedical application for microfluidic based devices has emerged in recent years and …
biomedical application for microfluidic based devices has emerged in recent years and …
Microfluidics: innovations in materials and their fabrication and functionalization
JB Nielsen, RL Hanson, HM Almughamsi… - Analytical …, 2019 - ACS Publications
Microfluidics is a growing field of study because these devices offer novel and versatile
approaches for addressing a range of scientific problems. Microfluidics have been used in …
approaches for addressing a range of scientific problems. Microfluidics have been used in …
Advances in engineering human tissue models
CM Moysidou, C Barberio, RM Owens - Frontiers in bioengineering …, 2021 - frontiersin.org
Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate
the investigation and understanding of specific biological events and processes under …
the investigation and understanding of specific biological events and processes under …
Organs-on-a-chip module: a review from the development and applications perspective
JE Sosa-Hernández, AM Villalba-Rodríguez… - Micromachines, 2018 - mdpi.com
In recent years, ever-increasing scientific knowledge and modern high-tech advancements
in micro-and nano-scales fabrication technologies have impacted significantly on various …
in micro-and nano-scales fabrication technologies have impacted significantly on various …
Engineered liver-on-a-chip platform to mimic liver functions and its biomedical applications: A review
J Deng, W Wei, Z Chen, B Lin, W Zhao, Y Luo, X Zhang - Micromachines, 2019 - mdpi.com
Hepatology and drug development for liver diseases require in vitro liver models. Typical
models include 2D planar primary hepatocytes, hepatocyte spheroids, hepatocyte …
models include 2D planar primary hepatocytes, hepatocyte spheroids, hepatocyte …
Organ-on-a-chip engineering: Toward bridging the gap between lab and industry
Organ-on-a-chip (OOC) is a very ambitious emerging technology with a high potential to
revolutionize many medical and industrial sectors, particularly in preclinical-to-clinical …
revolutionize many medical and industrial sectors, particularly in preclinical-to-clinical …
[HTML][HTML] Emerging biotechnology applications in natural product and synthetic pharmaceutical analyses
S Chen, Z Li, S Zhang, Y Zhou, X Xiao, P Cui… - … Pharmaceutica Sinica B, 2022 - Elsevier
Pharmaceutical analysis is a discipline based on chemical, physical, biological, and
information technologies. At present, biotechnological analysis is a short branch in …
information technologies. At present, biotechnological analysis is a short branch in …
[HTML][HTML] Emerging trends in organ-on-a-chip systems for drug screening
New drug discovery is under growing pressure to satisfy the demand from a wide range of
domains, especially from the pharmaceutical industry and healthcare services. Assessment …
domains, especially from the pharmaceutical industry and healthcare services. Assessment …
Organotypic cancer tissue models for drug screening: 3D constructs, bioprinting and microfluidic chips
Highlights•3D cultures are more advantageous than monolayers as biomimetics for drug
screening.•Bioprinting constructs complex tissue models that serve in vitro drug …
screening.•Bioprinting constructs complex tissue models that serve in vitro drug …