The integration of gene therapy into tissue engineering to control differentiation and direct
tissue formation is not a new concept; however, successful delivery of nucleic acids into …

Microspheres have long been used in drug delivery applications because of their controlled
release capabilities. They have increasingly served as the fundamental building block for …

Extracellular matrix (ECM)-based materials are attractive for regenerative medicine in their
ability to potentially aid in stem cell recruitment, infiltration, and differentiation without added …

Injectable gel systems, for the purpose of bone defect reconstruction, have many
advantages, such as controlled flowability, adaptability to the defect site, and increased …

To engineer bone tissue, an ideal biodegradable implant should be biocompatible,
biodegradable, osteoinductive and osteoconductive. However, the lack of bioactivity has …

Sustain release of drugs for a long period of time within a therapeutic range is the most
effective drug delivery system as it reduces the patient discomfort and compliance …

Microencapsulation and delivery of stem cells in biomaterials is a promising approach to
repairing damaged tissue in a minimally invasive manner. An appropriate biomaterial niche …

In this study, insulin‐like growth factor 1 (IGF‐1) was successfully immobilized on the poly
(lactide‐co‐glycolide)/hydroxyapatite (PLGA/HA) and pure PLGA microcarriers via …

Interfaces between soft tissue and bone are characterized by transitional gradients in
composition and structure that mediate substantial changes in mechanical properties. For …

The aim of this study was to fabricate mechanically functional microsphere‐based scaffolds
containing decellularized cartilage (DCC), with the hypothesis that this approach would …