Role of glutamine and its metabolite ammonia in crosstalk of cancer-associated fibroblasts and cancer cells
X Li, H Zhu, W Sun, X Yang, Q Nie, X Fang - Cancer cell international, 2021 - Springer
Abstract Cancer-associated fibroblasts (CAFs), the most abundant cells in the tumor
microenvironment, play an indispensable role in cancer initiation, progression, metastasis …
microenvironment, play an indispensable role in cancer initiation, progression, metastasis …
Metabolic reprogramming of glutamine involved in tumorigenesis, multidrug resistance and tumor immunity
W Xiao-Yan, Y Xiao-Xia, S Peng-Fei… - European Journal of …, 2023 - Elsevier
Glutamine, as the most abundant amino acid in the body, participates in the biological
synthesis of nucleotides and other non-essential amino acids in the process of cell …
synthesis of nucleotides and other non-essential amino acids in the process of cell …
Biallelic Dicer1 Mutations in the Gynecologic Tract of Mice Drive Lineage-Specific Development of DICER1 Syndrome–Associated Cancer
Y Wang, SY Chen, M Ta, J Senz, LV Tao, S Thornton… - Cancer Research, 2023 - AACR
DICER1 is an RNase III enzyme essential for miRNA biogenesis through cleaving precursor-
miRNA hairpins. Germline loss-of-function DICER1 mutations underline the development of …
miRNA hairpins. Germline loss-of-function DICER1 mutations underline the development of …
[HTML][HTML] NEDD4L inhibits cell viability, cell cycle progression, and glutamine metabolism in esophageal squamous cell carcinoma via ubiquitination of c-Myc: NEDD4L …
W Cheng, G Li, Z Ye, J Hu, L Gao, X Jia… - Acta Biochimica et …, 2022 - ncbi.nlm.nih.gov
Esophageal squamous cell carcinoma (ESCC) is a common subtype of esophageal cancer
with high incidence. Surgery remains the main strategy for treatment of ESCC at early stage …
with high incidence. Surgery remains the main strategy for treatment of ESCC at early stage …
Analysis of the glutamine dependent transaminases as possible therapeutic targets in colon cancer cells
Ș Bayram - 2024 - refubium.fu-berlin.de
The project's objective is to gain knowledge about the interconnection between cell growth
and metabolism in the colon cancer cells HCT116 and RKO that rely on glutamine's …
and metabolism in the colon cancer cells HCT116 and RKO that rely on glutamine's …
EXPLOITING GLUTAMINOLYSIS AS A THERAPEUTIC TARGET IN NON-HODGKIN LYMPHOMA
N Joseph - 2023 - qmro.qmul.ac.uk
Tumours rewire their metabolism to meet the increased biosynthetic and energetic demands
of proliferation. Many are critically reliant on glutamine metabolism, which offers an …
of proliferation. Many are critically reliant on glutamine metabolism, which offers an …