The eye contains a complex network of physiological information and biomarkers for
monitoring disease and managing health, and ocular devices can be used to effectively …

Age-related macular degeneration (AMD) is a blinding eye disease which incidence
gradually increases with age. Inflammation participates in AMD pathogenesis, including …

Age-related macular degeneration is a prevalent neuroinflammatory condition and a major
cause of blindness driven by genetic and environmental factors such as obesity. In diseases …

The retinal pigment epithelium (RPE) is a highly specialized, unique epithelial cell that
interacts with photoreceptors on its apical side and with Bruch's membrane and the …

Inflammation is a cellular response to factors that challenge the homeostasis of cells and
tissues. Cell-associated and soluble pattern-recognition receptors, eg Toll-like receptors …

Microglia, the primary resident immune cell type, constitute a key population of glia in the
retina. Recent evidence indicates that microglia play significant functional roles in the retina …

A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …

Purpose: Geographic atrophy (GA) is an advanced, vision-threatening form of age-related
macular degeneration (AMD) affecting approximately five million individuals worldwide. To …

Age-related macular degeneration (AMD) is the leading cause of legal blindness in the
industrialized world. AMD is characterized by accumulation of extracellular deposits, namely …

AMD is a major cause of legal blindness in older adults approachable through
multidisciplinary research involving human tissues and patients. AMD is a vascular …