Browning of the white adipose tissue regulation: New insights into nutritional and metabolic relevance in health and diseases

SA Machado, G Pasquarelli-do-Nascimento… - Nutrition & …, 2022 - Springer
Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining
health and homeostasis. Although white adipose tissue and brown adipose tissue are …

[HTML][HTML] Cerebral pressure autoregulation in brain injury and disorders–a review on monitoring, management, and future directions

TS Wettervik, M Fahlström, P Enblad, A Lewén - World neurosurgery, 2022 - Elsevier
The role of cerebral pressure autoregulation (CPA) in brain injury and disorders has gained
increased interest. The CPA is often disturbed as a consequence of acute brain injury, which …

Cerebral oxygen delivery and consumption in brain-injured patients

D Siwicka-Gieroba, C Robba, J Gołacki… - Journal of Personalized …, 2022 - mdpi.com
Organism survival depends on oxygen delivery and utilization to maintain the balance of
energy and toxic oxidants production. This regulation is crucial to the brain, especially after …

Fine tuning of traumatic brain injury management in neurointensive care—indicative observations and future perspectives

TM Svedung Wettervik, A Lewén, P Enblad - Frontiers in neurology, 2021 - frontiersin.org
Neurointensive care (NIC) has contributed to great improvements in clinical outcomes for
patients with severe traumatic brain injury (TBI) by preventing, detecting, and treating …

Cerebral blood flow and oxygen delivery in aneurysmal subarachnoid hemorrhage: relation to neurointensive care targets

T Svedung Wettervik, H Engquist, A Hånell, T Howells… - Neurocritical Care, 2022 - Springer
Background The primary aim was to determine to what extent continuously monitored
neurointensive care unit (neuro-ICU) targets predict cerebral blood flow (CBF) and delivery …

[HTML][HTML] Fine tuning of neurointensive care in aneurysmal subarachnoid hemorrhage: From one-size-fits-all towards individualized care

TS Wettervik, A Lewén, P Enblad - World Neurosurgery: X, 2023 - Elsevier
Aneurysmal subarachnoid hemorrhage (aSAH) is a severe type of acute brain injury with
high mortality and burden of neurological sequelae. General management aims at early …

Temperature changes in poor-grade aneurysmal subarachnoid hemorrhage: Relation to injury pattern, intracranial pressure dynamics, cerebral energy metabolism …

T Svedung Wettervik, A Hånell, E Ronne-Engström… - Neurocritical Care, 2023 - Springer
Background The aim was to study the course of body temperature in the acute phase of poor-
grade aneurysmal subarachnoid hemorrhage (aSAH) in relation to the primary brain injury …

Traumatic brain injury extending to the striatum alters autonomic thermoregulation and hypothalamic monoamines in recovering rats

A Verduzco-Mendoza, D Mota-Rojas… - Frontiers in …, 2023 - frontiersin.org
The brain cortex is the structure that is typically injured in traumatic brain injury (TBI) and is
anatomically connected with other brain regions, including the striatum and hypothalamus …

Lactate shuttling as an allostatic means of thermoregulation in the brain

DA Kane, ACY Foo, EB Noftall, K Brebner… - Frontiers in …, 2023 - frontiersin.org
Lactate, the redox-balanced end product of glycolysis, travels within and between cells to
fulfill an array of physiologic functions. While evidence for the centrality of this lactate …

Cerebral microdialysis monitoring of energy metabolism: relation to cerebral blood flow and oxygen delivery in aneurysmal subarachnoid hemorrhage

TS Wettervik, H Engquist, A Hånell… - Journal of …, 2023 - journals.lww.com
Methods: Fifty-seven adult aSAH patients treated on the neurointensive care unit at Uppsala,
Sweden between 2012 and 2020, with at least 1 xenon-enhanced computed tomography …