Metabolic reprogramming is a new hallmark of cancer but it remains poorly defined in
hepatocellular carcinogenesis (HCC). The fatty acid receptor CD36 is associated with both …

Cell metabolism can be reprogrammed by tissue hypoxia leading to cell transformation and
glioblastoma multiforme (GBM) progression. In response to hypoxia, GBM cells are able to …

Breast cancer cells frequently home to the bone marrow, where they may enter a dormant
state before forming a bone metastasis. Several members of the interleukin-6 (IL-6) cytokine …

Renal cell carcinoma is the most common form of the kidney cancer accounting for more
than 85% of the cases of which clear cell renal cell carcinoma (ccRCC) is the major …

Triple-negative breast cancer (TNBC) is notoriously aggressive with high metastatic
potential, which has recently been linked to high rates of fatty acid oxidation (FAO). Here we …

The tripartite motif (TRIM) family comprises more than 70 members involved in the regulation
of many cellular pathways. TRIM 32 acts as an E3 ubiquitin ligase and has been reported to …

Background Considering the involvement of genetics in migraine pathogenesis in diverse
ethnic populations, genome-wide association studies (GWAS) are being conducted to …

The understanding of the pathogenesis of renal cell carcinoma led to the development of
targeted therapies, which dramatically changed the overall survival rate. Nonetheless …

Triple-negative breast cancer (TNBC) is a highly aggressive and metastatic form of breast
cancer that lacks the estrogen, progesterone and HER2 receptors and is resistant to …

Background Kidney organoids derived from human pluripotent stem cells (HiPSCs) hold
huge applications for drug screening, disease modeling, and cell transplanting therapy …