Although glutamate is one of the most important excitatory neurotransmitters of the central
nervous system, its excessive extracellular concentration leads to uncontrolled continuous …

Glaucoma is the second leading cause of blindness worldwide, affecting~ 80 million people
by 2020 (,). The condition is characterized by a progressive loss of retinal ganglion cells …

In the last years, neuroprotective therapies have attracted the researcher interests as
modern and challenging approach for the treatment of neurodegenerative diseases, aimed …

Glaucoma, a leading cause of blindness worldwide, is characterized by progressive optic
nerve damage, usually associated with intraocular pressure. Although the clinical …

Background: Emerging neuroprotective strategies are being explored to preserve the retina
from degeneration, that occurs in eye pathologies like glaucoma, diabetic retinopathy, age …

Glaucoma is a complex group of diseases wherein a selective degeneration of retinal
ganglion cells (RGCs) lead to irreversible loss of vision. A comprehensive approach to …

Optic neuropathy refers to dysfunction and/or degeneration of axons of the optic nerve with
subsequent optic nerve atrophy. A common feature of different optic neuropathies is retinal …

A preferential loss of retinal ganglion cells (RGCs) is observed in glaucoma and optic
neuritis. Loss of tropomyosin-related kinase receptor B (TrkB)-mediated signaling has been …

Background aims The purpose of this study was to investigate the neuroprotective effects of
bone marrow bone marrow–derived and adipose tissue–derived mesenchymal stromal cells …

Due to a prolonged life expectancy worldwide, the incidence of age-related
neurodegenerative disorders such as glaucoma is increasing. Glaucoma is the second …