Recent advances in active targeting of nanomaterials for anticancer drug delivery
One of the challenges in cancer chemotherapy is the low target to non-target ratio of
therapeutic agents which incur severe adverse effect on the healthy tissues. In this regard …
therapeutic agents which incur severe adverse effect on the healthy tissues. In this regard …
Stimuli-responsive nano-architecture drug-delivery systems to solid tumor micromilieu: past, present, and future perspectives
The microenvironment characteristics of solid tumors, renowned as barriers that harshly
impeded many drug-delivery approaches, were precisely studied, investigated, categorized …
impeded many drug-delivery approaches, were precisely studied, investigated, categorized …
Surface functionalization and targeting strategies of liposomes in solid tumor therapy: A review
MK Riaz, MA Riaz, X Zhang, C Lin, KH Wong… - International journal of …, 2018 - mdpi.com
Surface functionalization of liposomes can play a key role in overcoming the current
limitations of nanocarriers to treat solid tumors, ie, biological barriers and physiological …
limitations of nanocarriers to treat solid tumors, ie, biological barriers and physiological …
Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery
VP Torchilin - Nature reviews Drug discovery, 2014 - nature.com
The use of nanoparticulate pharmaceutical drug delivery systems (NDDSs) to enhance the
in vivo effectiveness of drugs is now well established. The development of multifunctional …
in vivo effectiveness of drugs is now well established. The development of multifunctional …
Nanocarriers for cancer-targeted drug delivery
Nanoparticles as drug delivery system have received much attention in recent years,
especially for cancer treatment. In addition to improving the pharmacokinetics of the loaded …
especially for cancer treatment. In addition to improving the pharmacokinetics of the loaded …
Current trends in the use of liposomes for tumor targeting
The use of liposomes for drug delivery began early in the history of pharmaceutical
nanocarriers. These nanosized, lipid bilayered vesicles have become popular as drug …
nanocarriers. These nanosized, lipid bilayered vesicles have become popular as drug …
Ligand-targeted liposome design: challenges and fundamental considerations
GT Noble, JF Stefanick, JD Ashley, T Kiziltepe… - Trends in …, 2014 - cell.com
Nanomedicine, particularly liposomal drug delivery, has expanded considerably over the
past few decades, and several liposomal drugs are already providing improved clinical …
past few decades, and several liposomal drugs are already providing improved clinical …
Biomimetic cell-derived nanocarriers in cancer research
Nanoparticles have now long demonstrated capabilities that make them attractive to use in
biology and medicine. Some of them, such as lipid nanoparticles (SARS-CoV-2 vaccines) or …
biology and medicine. Some of them, such as lipid nanoparticles (SARS-CoV-2 vaccines) or …
Barriers to drug delivery in solid tumors
SK Sriraman, B Aryasomayajula, VP Torchilin - Tissue barriers, 2014 - Taylor & Francis
Over the last decade, significant progress has been made in the field of drug delivery. The
advent of engineered nanoparticles has allowed us to circumvent the initial limitations to …
advent of engineered nanoparticles has allowed us to circumvent the initial limitations to …
Nanodrug delivery in reversing multidrug resistance in cancer cells
S Kapse-Mistry, T Govender, R Srivastava… - Frontiers in …, 2014 - frontiersin.org
Different mechanisms in cancer cells become resistant to one or more chemotherapeutics is
known as multidrug resistance (MDR) which hinders chemotherapy efficacy. Potential …
known as multidrug resistance (MDR) which hinders chemotherapy efficacy. Potential …