IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy
Microglia shift toward an inflammatory phenotype during aging that is thought to exacerbate
age-related neurodegeneration. The molecular and cellular signals that resolve …
age-related neurodegeneration. The molecular and cellular signals that resolve …
Meiotic drive in house mice: mechanisms, consequences, and insights for human biology
Meiotic drive occurs when one allele at a heterozygous site cheats its way into a
disproportionate share of functional gametes, violating Mendel's law of equal segregation …
disproportionate share of functional gametes, violating Mendel's law of equal segregation …
Rare functional genetic variants in COL7A1, COL6A5, COL1A2 and COL5A2 frequently occur in Chiari Malformation Type 1
A Urbizu, ME Garrett, K Soldano, O Drechsel, D Loth… - PLoS …, 2021 - journals.plos.org
Chiari Malformation Type 1 (CM-1) is characterized by herniation of the cerebellar tonsils
below the foramen magnum and the presence of headaches and other neurologic …
below the foramen magnum and the presence of headaches and other neurologic …
[HTML][HTML] Disentangling archaic introgression and genomic signatures of selection at human immunity genes
A Urnikyte, A Masiulyte, L Pranckeniene… - Infection, Genetics and …, 2023 - Elsevier
Pathogens and infectious diseases have imposed exceptionally strong selective pressure
on ancient and modern human genomes and contributed to the current variation in many …
on ancient and modern human genomes and contributed to the current variation in many …
[HTML][HTML] A mouse model of the 3-hit effects of stress: Genotype controls the effects of life adversities in females
L Babicola, C Mancini, C Riccelli, M Di Segni… - Progress in Neuro …, 2023 - Elsevier
Helplessness is a dysfunctional coping response to stressors associated with different
psychiatric conditions. The present study tested the hypothesis that early and adult …
psychiatric conditions. The present study tested the hypothesis that early and adult …