Significant improvements in disease management have been achieved in the past few
decades. Using cancer as an example, survival rates have increased dramatically in …

We present a novel efficient method for the synthesis of substituted arylidene‐1‐H‐imidazol‐
5‐(4H)‐ones based on the use of azidoacetic acid amides. The proposed approach was …

ECFP, the first usable cyan fluorescent protein (CFP), was obtained by adapting the tyrosine-
based chromophore environment in green fluorescent protein to that of a tryptophan-based …

We synthesized 2′-deoxycytidine and the corresponding nucleoside triphosphate bearing
(indol-3-yl) methylene-2-methyl-5-oxo-4, 5-dihydroimidazol-1-yl group (a tryptophan-based …

Objective: Synthesis of a series of methylene-imidazolones with complexing groups.
Methods: The formation of imines with the following [2+ 3]-cycloaddition and recycling. The …

The aim of the thesis was to synthesize new nucleosides, nucleotides and the
corresponding DNA probes bearing various fluorescent labels, which can be used for …

Aequorea victoria-based green fluorescent proteins and their blue, cyan and red
counterparts offer unprecedented advantage as biological markers owing to their genetic …

Chromophore structures inspired by natural green fluorescent protein (GFP) play an
important role in the field of bio-imaging. In this work, photochemical properties of a new …

Новое производное хромофора зеленого флуоресцентного белка (Z)-5-((E)-4-(4-
гидроксифенил) аллилиден)-2, 3-диметил-3, 5-дигидро-4H-имидазол-4-он, было …

A novel derivative of green fluorescent protein chromophore (Z)-5-((E)-3-(4-hydroxyphenyl)
allylidene)-2, 3-dimethyl-3, 5-dihydro-4 H-imidazol-4-one was synthesised. The desired …