Usher syndrome (USH) is the most common cause of deaf–blindness in humans, with a
prevalence of about 1/10,000 (~ 400,000 people worldwide). Cochlear implants are …

This article is the second of eight articles in this special issue on Family-Centered Early
Intervention (FCEI) for children who are deaf or hard of hearing (DHH) and their families, or …

Usher syndrome type 1B (USH1B) is a deaf-blindness disorder, caused by mutations in the
MYO7A gene, which encodes the heavy chain of an unconventional actin-based motor …

Usher syndrome is the most common cause of deafness-blindness in the world. Usher
syndrome type 1B (USH1B) is associated with mutations in MYO7A. Patients with USH1B …

Importance A genetic diagnosis can help elucidate the prognosis of hearing loss, thus
significantly affecting management. Previous studies on diagnostic yield of hearing loss …

Inner ear disorders have a variety of causes, and many factors can contribute to the
exacerbation of cochlear and vestibular pathology. This systematic review aimed to analyze …

Abstract Translocator protein (18 kDa)(Tspo), formerly known as peripheral benzodiazepine
receptor is a highly conserved transmembrane protein primarily located in the outer …

Usher syndrome (USH) is the leading cause of combined deafness-blindness with type 2 A
(USH2A) being the most common form. Knockout models of USH proteins, like the Ush2a …

Retinitis pigmentosa (RP) is a progressive inherited retinal dystrophy, characterized by the
degeneration of photoreceptors, presenting as a rod-cone dystrophy. Approximately 20-30 …

Background Prenatal alcohol (ethanol) exposure (PAE) results in brain growth restriction, in
part, by reprogramming self-renewal and maturation of fetal neural stem cells (NSCs) during …