Current perspectives on Stevens-Johnson syndrome and toxic epidermal necrolysis

M Lerch, C Mainetti, B Terziroli Beretta-Piccoli… - Clinical reviews in …, 2018 - Springer
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are considered a
delayed-type hypersensitivity reaction to drugs. They represent true medical emergencies …

Corneal neovascularization

MP Nicholas, N Mysore - Experimental eye research, 2021 - Elsevier
The optical clarity of the cornea is essential for maintaining good visual acuity. Corneal
neovascularization, which is a major cause of vision loss worldwide, leads to corneal …

Corneal neovascularization: an anti-VEGF therapy review

JH Chang, NK Garg, E Lunde, KY Han, S Jain… - Survey of …, 2012 - Elsevier
Corneal neovascularization is a serious condition that can lead to a profound decline in
vision. The abnormal vessels block light, cause corneal scarring, compromise visual acuity …

[HTML][HTML] Pharmacokinetics of bevacizumab after topical, subconjunctival, and intravitreal administration in rabbits

H Nomoto, F Shiraga, N Kuno, E Kimura… - … & visual science, 2009 - iovs.arvojournals.org
purpose. To investigate the pharmacokinetics of bevacizumab in rabbits for three different
routes of administrations: intravitreal injection, subconjunctival injection, and eye drops …

Limiting angiogenesis to modulate scar formation

S Korntner, C Lehner, R Gehwolf, A Wagner… - Advanced Drug Delivery …, 2019 - Elsevier
Angiogenesis, the process of new blood vessel formation from existing blood vessels, is a
key aspect of virtually every repair process. During wound healing an extensive, but …

Topical bevacizumab in the treatment of corneal neovascularization: results of a prospective, open-label, noncomparative study

MH Dastjerdi, KM Al-Arfaj, N Nallasamy… - Archives of …, 2009 - jamanetwork.com
Objective To study the safety and efficacy of topical bevacizumab in the treatment of corneal
neovascularization (NV). Design In a prospective, open-label, noncomparative study, 10 …

Novel aspects of corneal angiogenic and lymphangiogenic privilege

D Ellenberg, DT Azar, JA Hallak, F Tobaigy… - Progress in retinal and …, 2010 - Elsevier
In this article, we provide the results of experimental studies demonstrating that corneal
avascularity is an active process involving the production of anti-angiogenic factors, which …

Modulating the tachykinin: Role of substance P and neurokinin receptor expression in ocular surface disorders

RB Singh, A Naderi, W Cho, G Ortiz, A Musayeva… - The ocular …, 2022 - Elsevier
Substance P (SP) is a tachykinin expressed by various cells in the nervous and immune
systems. SP is predominantly released by neurons and exerts its biological and …

Treatments for corneal neovascularization: a review

D Gupta, C Illingworth - Cornea, 2011 - journals.lww.com
Corneal neovascularization (CNV) may be a physiological response to various stimuli, but a
chronic and persistent upregulation of neoangiogenesis can result in pathological CNV …

Therapeutic contact lenses for the treatment of corneal and ocular surface diseases: advances in extended and targeted drug delivery

B Abdi, M Mofidfar, F Hassanpour, EK Cilingir… - International journal of …, 2023 - Elsevier
The eye is one of the most important organs in the human body providing critical information
on the environment. Many corneal diseases can lead to vision loss affecting the lives of …