Olfactory ensheathing cells for spinal cord injury: sniffing out the issues
R Yao, M Murtaza, JT Velasquez… - Cell …, 2018 - journals.sagepub.com
Olfactory ensheathing cells (OECs) are glia reported to sustain the continuous axon
extension and successful topographic targeting of the olfactory receptor neurons …
extension and successful topographic targeting of the olfactory receptor neurons …
Multi-target approaches to CNS repair: olfactory mucosa-derived cells and heparan sulfates
SL Lindsay, GA McCanney, AG Willison… - Nature Reviews …, 2020 - nature.com
Spinal cord injury (SCI) remains one of the biggest challenges in the development of
neuroregenerative therapeutics. Cell transplantation is one of numerous experimental …
neuroregenerative therapeutics. Cell transplantation is one of numerous experimental …
Chlamydia pneumoniae can infect the central nervous system via the olfactory and trigeminal nerves and contributes to Alzheimer's disease risk
Chlamydia pneumoniae is a respiratory tract pathogen but can also infect the central
nervous system (CNS). Recently, the link between C. pneumoniae CNS infection and late …
nervous system (CNS). Recently, the link between C. pneumoniae CNS infection and late …
Phagocytosis by peripheral glia: Importance for nervous system functions and implications in injury and disease
The central nervous system (CNS) has very limited capacity to regenerate after traumatic
injury or disease. In contrast, the peripheral nervous system (PNS) has far greater capacity …
injury or disease. In contrast, the peripheral nervous system (PNS) has far greater capacity …
Olfactory ensheathing cells are the main phagocytic cells that remove axon debris during early development of the olfactory system
L Nazareth, KE Lineburg, MI Chuah… - Journal of …, 2015 - Wiley Online Library
During development of the primary olfactory system, axon targeting is inaccurate and axons
inappropriately project within the target layer or overproject into the deeper layers of the …
inappropriately project within the target layer or overproject into the deeper layers of the …
Burkholderia pseudomallei penetrates the brain via destruction of the olfactory and trigeminal nerves: implications for the pathogenesis of neurological melioidosis
Melioidosis is a potentially fatal disease that is endemic to tropical northern Australia and
Southeast Asia, with a mortality rate of 14 to 50%. The bacterium Burkholderia pseudomallei …
Southeast Asia, with a mortality rate of 14 to 50%. The bacterium Burkholderia pseudomallei …
The migration of olfactory ensheathing cells during development and regeneration
The primary olfactory nervous system is unique in that it continuously renews itself and
regenerates after injury. These properties are attributed to the presence of olfactory glia …
regenerates after injury. These properties are attributed to the presence of olfactory glia …
Clinical cell therapy guidelines for neurorestoration (IANR/CANR 2017)
H Huang, W Young, L Chen, S Feng… - Cell …, 2018 - journals.sagepub.com
Cell therapy has been shown to be a key clinical therapeutic option for central nervous
system diseases or damage. Standardization of clinical cell therapy procedures is an …
system diseases or damage. Standardization of clinical cell therapy procedures is an …
Low-dose curcumin stimulates proliferation, migration and phagocytic activity of olfactory ensheathing cells
One of the promising strategies for neural repair therapies is the transplantation of olfactory
ensheathing cells (OECs) which are the glial cells of the olfactory system. We evaluated the …
ensheathing cells (OECs) which are the glial cells of the olfactory system. We evaluated the …
Optimizing olfactory ensheathing cell transplantation for spinal cord injury repair
AD Gilmour, R Reshamwala, AA Wright… - Journal of …, 2020 - liebertpub.com
Cell transplantation constitutes an important avenue for development of new treatments for
spinal cord injury (SCI). These therapies are aimed at supporting neural repair and/or …
spinal cord injury (SCI). These therapies are aimed at supporting neural repair and/or …